DISSEMINATED INTRAVASCULAR COAGULATION

Authors

  • Humaira Naz
  • Anisa Fawad
  • Ansa Islam
  • Hamna Shahid
  • Aziz -un-Nisa Abbasi

Abstract

Background: Disseminated Intravascular Coagulation (DIC) is a complex systemic thrombohaemorrhagic disorder characterised by widespread endothelial damage. Aim of this study was to assessthe prevalence of DIC in different obstetrical conditions. Methods: This descriptive study was carriedout in the Department of Obstetrics and Gynaecology Unit ‘A’, Ayub Medical College, Abbottabad fromJanuary 2010 to December 2011. All 40 diagnosed cases of DIC were included, and their risk factors andmaternal/foetal outcome were evaluated. Results: Out of 4,334 obstetrical admissions, DIC wasdiagnosed in 40 (0.92%) patients. Risk factors noted were eclampsia 28 (70%), abruptio placentae 7(17.5%), septicaemia 3 (7.5%), pancytopenia 1 (2.5%), and 1 (2.5%) patient had DIC secondary tohaemorrhagic shock due to placenta previa. Mean age range of patients was 31±6.69 (19–48) year, andparity was 3.17±2.56 (0–10). Mode of delivery of 34 (85%) patients was by caesarean section, andvaginal delivery occurred in 3 (7.5%) patients. Eleven (27.5%) patients had caesarean hysterectomy.Maternal mortality was 25% and perinatal mortality was (47.5%). Majority of our patients were criticaland were managed in ICU. Conclusion: DIC is serious life threatening condition secondary to anyunderlying pathology. There is spontaneous resolution of DIC after correction of pathology.Keywords: DIC, Eclampsia, Abruptio placentae, placenta previa, haemorrhagic shock

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Published

2011-12-01

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