CAROTID DISEASE IN DIABETIC PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFTING
AbstractObjective: To compare the severity of carotid artery disease in diabetic and non-diabetic patientsundergoing coronary artery bypass grafting. Methods: From January to June 2008, 379 patientsundergoing elective coronary artery bypass surgery were preoperatively evaluated for the presence ofcarotid stenoses by duplex scanning. Patients were divided into two groups, Group I, 156 (41.2%)diabetic patients and Group II, 223 (58.8%) non-diabetic patients. Results: There were 314 (82.8%)males and 65 (17.2%) females with a mean age of 57.2±9.1 years. In diabetic group there were 125(80.1%) males and 31 (19.9%) females with a mean age of 56.3±8.9 years. Left main stem stenosis waspresent in 59 (37.8%) diabetics and 45 (20.2%) non-diabetics (p<0.0001). Diffuse disease in leftanterior descending (LAD) artery was observed in more diabetic patients 72 (46.2%) as compared tonon-diabetics 83 (37.2%) (p<0.295). Single tight stenosis in LAD was observed in more non-diabetics.Significant carotid artery stenosis was observed in 50 (13.2%) patients. Carotid artery stenosis wasobserved in 30 (19.2%) diabetics as compared to 20 (9%) non-diabetics (p<0.004). Analysis ofpercentage stenosis of carotid artery disease in the study population revealed that >70% stenosis waspresent in 20 (5.3%) with 13 (8.3%) diabetics and 7 (3.1%) non-diabetics (p<0.025). Stenosis of 50–70% was observed in 30 (7.9%) of which 17 (10.9%) were diabetics and 13 (5.8%) were non-diabetics.Conclusion: Presence of diabetes mellitus is associated with diffuse coronary artery disease andsignificant carotid artery disease in patients undergoing coronary artery bypass grafting.Keywords: Atherosclerosis, Coronary artery disease, Carotid artery disease, Coronary arterybypass grafting, Diabetes Mellitus
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