• Muhammad Saeed
  • Inam -ul- Haq
  • Muhammad Amer Saleem


Background: To assess the gender-based differences in the echocardiographic outcomes of patientswith mitral stenosis presenting at a tertiary care hospital and the clinical implications of suchdifferences. Methods: A total of 90 echocardiographs of both men and women (aged≥15 years) havingmitral valve area (MVA) less than 4 cm2 were assessed. In addition to MVA, pressure half time and leftatrial diameter (LAD) of the patients was also recorded. Other co-existing valvular lesions were alsoassessed in addition to mitral stenosis. Statistical analysis was done using SPSS-17. Results: A higherprevalence of mitral stenosis (MS) was found in women than men (76.66% vs 24.44%). Men werehaving more severe mitral stenosis as compared to women (MVA=1.19 cm2 vs 1.32 cm2). This alsoresulted in significantly higher left atrial dilatation in males as compared to women (45.09 vs 41.75,p=0.0422). Most of the patients had other coexisting valvular lesions and isolated MS was rare.However, men had a predominance of aortic stenosis along with mitral stenosis (27% vs 4%, p=0.0059)whereas women had a higher prevalence of mitral regurgitation along with mitral stenosis than the men(65% vs 36%, p=0.0258). Conclusion: There were certain significant differences in echocardiographicoutcomes of patients based upon their gender. A gender-specific management approach towards thepatients with mitral stenosis is essential to have better outcome.Keywords: Mitral stenosis, Rheumatic heart disease, Echocardiography, Gender


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