FREQUENCY OF VISCERAL LEISHMANIASIS IN ABBOTTABAD FROM 2005 TO 2009

Authors

  • Seema Nadeem
  • Sabah Shamroz
  • Touqueer Iqbal
  • Modood ul Manan
  • Abdus Salaam

Abstract

Background: Leishmaniasis is a parasitic disease caused by a haemoflagellate Leishmania, transmittedto humans through bites of female sand fly. The objective of this study was to assess the frequency ofleishmaniasis in Abbottabad and nearby areas including villages of Nawanshehr, Dhodial, Gamavan,Sheikhulbandi, Kakul and Malikpura. Method: This was a retrospective study carried out in PathologyDepartment, Women Medical College and Benazir Bhutto Teaching Hospital Abbottabad from 2005 to2009. The diagnosis was based on intracellular and extracellular amastigote forms of Leishmaniadonovani in the bone marrow aspirates. Results: We diagnosed 61 cases of visceral leishmaniasis,mostly from Nawanshehr (32.78%), in children below 5 years of age with febrile splenomegaly.Conclusion: The disease is gradually spreading southwards in the country. A high index of suspicionshould be kept in mind for all cases coming from Northern Areas of the country where the frequency isquite high. Local health authorities should take drastic action against this spreading disease.Keywords: visceral leishmaniasis, bone marrow, leishmaniasis

References

S Singh, R Sivakumar. Recent advances in the diagnosis of

leishmaniasis. R J Postgrad Med 2003;49(1):55–60.

Tanoli ZM, Rai ME, Salam A. Clinical Presentation and

Management of Visceral Leishmaniasis. J Ayub Med Coll

Abbottabad 2005;17(4):51–3.

J Ayub Med Coll Abbottabad 2010;22(3)

http://www.ayubmed.edu.pk/JAMC/PAST/22-3/Seema.pdf

Mauricio IL, Howard MK, Stothard JR, Miles MA. Genomic

diversity in the Leishmania donovani complex. Parasitology

;119( Pt 3):237–46.

Sundar S, Rai M. Laboratory Diagnosis of Visceral

Leishmaniasis. Clin Diagn Lab Immunol 2002;9(5):951–8.

Hoffbrand AV, Pettit JE. (Eds) Visceral Leishmaniasis. In:

Essential Haematology, 5th Edition, USA: Backwell; 2007.p.

Barbara Bain B, S Mitchell Lewis. Preparation and staining

methods for blood and bone marrow films. In: Dacie and

Lewis Practical Haematology,10th Edition, Philadelphia:

Elsevier Ltd; 2006.p. 74.

Thornton SJ, Wasan KM, Piecuch A, Lynd LL, Wasan EK.

Barriers to treatment for visceral leishmaniasis in

hyperendemic areas: India, Bangladesh, Nepal, Brazil and

Sudan. Drug Dev Ind Pharm 2010;36:1312–9.

Bora D. Epidemiology of visceral leishmaniasis in India. Natl

Med J India 1999;12(2):62–8.

Ready PD. Leishmaniasis emergence in Europe. Euro

Surveill 2010;15:19505.

World Health Organisation action in Afghanistan aims to control

debilitating leishmaniasis. Geneva, 2004. Available from:

http://www.who.int/mediacentre/news/releases/2004/pr55/en/

index.html

Pizzuto M, Piazza M, Senese D, Scalamogna C, Calattini S,

Corsico L, et al. Role of PCR In Diagnosis and prognosis of

visceral leshmaniasis in patients coinfected with Human

Immunodeficiency Virus Type 1. J Clin Microbiol

;39(1):357–61.

Romero GAS, Boelaert M. Control of visceral leshmaniasis

in Latin America. PLoS Negl Trop Dis 2010; 4(1):e584.

Abdur Rab, David A. Leishmania infantum in the Himalayas.

Tropical Medicine and Hygiene 1994;89(1):27–32.

Kakarsulemankhel JK Present situation of Cutaneous

Leishmaniasis in Balochistan, Pakistan. Pak J Biol Sci

;7(5):698–702.

Mannan MU, Yousaf M, Idrees M. Focus of visceral

leshmaniasis in District Abbottabad. J Ayub Med Coll

Abbottabad 2000;12(2):17–8.

Rai ME, Muhammad Z, Hematological Finding in relation to

Clinical Finding of Visceral Leishmaniasis in Hazara

Division. J Ayub Med Coll Abbottabad 2008;20(3):40–3.

Downloads

Published

2010-09-01