• Nadeem Ullah
  • Muhammad Usman
  • Abdur Rehman Khan


Background: The foetus has become increasingly accessible and visible as a patient over the last twodecades. Ultrasound imaging has broadened the scope of foetal assessment. Dynamic real time B-Modeultrasound is used to monitor cluster of biophysical variables, both dynamic and static collectivelytermed as biophysical profile. The purpose of this study was to determine the effect of sonographicbiophysical profile score on perinatal outcome in terms of mortality and morbidity. Methods: Thisdescriptive study was carried on 100 randomly selected high risk pregnant patients in RadiologyDepartment PGMI, Government Lady Reading Hospital, Peshawar from December 2007 to June 2008.Manning biophysical profile including non-stress was employed for foetal screening, using Toshibaultrasound machine model Nemio SSA-550A and 7.5 MHZ probe. Results: Out of 100 cases 79 (79%)had a normal biophysical profile in the last scan of 10/10 and had a normal perinatal outcome with 5minutes Apgar score >7/10. In 13 (13%) cases Apgar score at 5 minute was < 7/10 and babies wereshifted to nursery. There were 2 (2%) false positive cases that showed abnormal biophysical profilescores of 6/10 but babies were born with an Apgar score of 8/10 at 5 minutes. There were 2 (2%)neonatal deaths in this study group. The sensitivity of biophysical profile was 79.1%, specificity 92.9%.Predictive value for a positive test was 98.55%; predictive value for a negative test was 41.93%.Conclusion: Biophysical profile is highly accurate and reliable test of diagnosing foetal hypoxia.Keywords: Foetal biophysical profile, High risk pregnancy, Perinatal outcome


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