SURGICAL SITE INFECTION AND PATTERN OF ANTIBIOTIC USE IN A TERTIARY CARE HOSPITAL IN PESHAWAR
AbstractBackground: Surgical site infection (SSI) is most common complication following surgicalprocedures. The objective of the study was to collect information on SSI regarding the most frequentpathogen in cases operated in casualty of Lady Reading Hospital (LRH) Peshawar, and sensitivity ofthe isolated pathogens to different antibiotics used. Methods: The study was carried out at surgical ‘B’unit (SBU) LRH from Jan 1, 2009 till Dec 31, 2009. A total of 100 patients who developed SSI afterbeing operated for peritonitis following traumatic gut perforations, perforated appendix and entericperforation. The patients included presented to casualty, operated in casualty OT and were shifted to theSBU, LRH. Children and patients operated on the elective list were excluded. Data was collected onspecially designed proforma. Demographic details, details of SSI, culture/sensitivity reports andantibiotic used for prophylaxis and after C/S report were recorded. Results: Out of a total of 100, 72had superficial, 20 had organ/space and 8 had deep SSI. Organisms were isolated in 77 cases (77%). E.coli being most common pathogen (46%), followed by Pseudomonas (23%), mixed growth of Staph.Aureus or MRSA (13%), MRSA (5%) AND Staph aureus (4%) in descending order. No growth wasreported in 23% of cases. Conclusion: E.coli was the most common organism involved in SSI in SBULRH. The incidence of infection with MRSA in our unit is high. Combination of antibiotics likepipreacillin/Tazobactam, Cefoperazone/Sulbactam, were most effective against the isolated organisms,except MRSA where Linezolid , vancomycin and Tiecoplanin were effective.Keywords: Surgical site infection (SSI), antibiotics, drug resistance
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