• Ghayyur Khan
  • Nasir Khan
  • Abdul Aziz


Background: Diabetes is a metabolic disorder that affects many systems in the body. Cerebralatrophy is one of the complications of diabetes and research is on going to find out itsaetiopathological factors. The main aim of the study was to determine the frequency of cerebralatrophy in type-II diabetes mellitus using magnetic resonance imaging of the brain. Methods: Onehundred diabetic patients (Random blood sugar >126 mg/dl) were recruited in this study after theinformed consent from every patient. Duration of diabetes was five years and more in all the patientsas determined by their glycosylated haemoglobin which was >6 in all the patients. All the patientswere undergone MRI of brain using 1.5 Tesla power magnetic resonance imaging machine of PickerCompany. Evan’s index, a specific parameter for measurement of cerebral atrophy was calculated onMR images and was used in this study. Results: In male group the frequency of cerebral atrophy was22 (47%) and in female group it was found to be 23 (43%). When we study the overall populationthe frequency was found to be 45 (45%). The results are well in concordance with the previous datapublished on this issue. Conclusions: Cerebral atrophy, a complication of long standing diabetes isquite frequent in our population and is well diagnosed by MRI.Keywords: Diabetes Mellitus, cerebral atrophy, MRI, frequency, complications of diabetes


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