• Sher Bahadar Khan
  • Lubna Noor
  • Hafiz -ur- Rehman
  • Hameed ullah
  • Mohammad Hafeezullah
  • Zahid Aslam Awan
  • Shahab ud Din
  • Syed Sadiq Shah


Background: Globally, obesity is now recognised as an epidemic. The degree of obesity isproportional to the rate of development of cardiovascular diseases, hence, resulting in a dramaticincrease in morbidity and mortality. Apart from obesity, hypertension is another well recognised riskfactor contributing to coronary artery disease (CAD). The precise prevalence of obesity-relatedhypertension varies with age, race and gender; and is yet unknown in our population. The objective ofthis study was to determine the prevalence of hypertension in obese and non-obese patients withdiagnosed CAD. Methods: This hospital based descriptive study was conducted in CardiologyDepartment of Postgraduate Medical Institute, Lady Reading Hospital, Peshawar from 15th March 2007to 30th May 2008. A total of 200 patients with diagnosed CAD were enrolled, 100 were found obeseand 100 non-obese. Results: Among these, a total of 111 (55.5%) were found to be hypertensive, 66(59.46%) of these were obese and 45 (40.54%) non-obese (p=0.003). Conclusion: Obese patients withCAD had significantly more frequent hypertension.Keywords: Coronary Artery Disease, CAD, Body Mass Index, BMI, Obesity, Hypertension


Abbas S, Shazia A, Riaz A, Malik N. Risk factors for CAD

in Pakistan. Pak Armed Forces Med J 2003;53:12–9.

Samad A, Sahibzada WA, Mattu A. Risk factor analysis in

random population of 4 cities in Pakistan. Pak J Cardiol


Aziz-ur-Rahman, Sattar A, Abaidullah S, Hassan M.

Evaluation of cardiovascular risk factors in patient with

essential hypertension. Ann KE Med Coll 1999;5:134–-7.

Thomas F, Bean K, Pannier B, Oppert JM, Guize L, Benetos

A. Cardiovascular mortality in overweight subjects. The key

role of associated risk factors. Hypertension 2005;46:654–5.

Zahid A. Genetic aspects of human obesity. J Pak Med Assoc


World Health Organization. WHO world wide health report:

Reducing risks promoting healthy life. Geneva: World Health

Organization; 2002.

World Health Organization. WHO Reports 2004, WHO

global NCD infobase [Online] 2004 [Cited on August 13,

. URL: http//

Dawber TR. The Fragmington study: the epidemiology of

Atherosclerotic disease. Cambridge: Harvard University

press; 1980.p.257.

Dyer AR, Elliott P, Shipley M. Body mass index versus

height and weight in relation to blood pressure. Findings for

the 10,079 persons in the INTERSALT Study. Am J

Epidemiol 1990;131:589–96.

MacMahon SW, Blacket RB, Macdonald GJ, Hall W.

Obesity, alcohol consumption and blood pressure in

Australian men and women. The National Heart Foundation

of Australia Risk Factor Prevalence Study. J Hypertens


MacMahon S, Cutler J, Brittain E, Higgins M. Obesity and

hypertension: epidemiological and clinical issues. Eur Heart J

;8(Suppl B):57–70

Garrison RJ, Kannel WB, Stokes J 3rd, Castelli WP.

Incidence and precursors of hypertension in young adults: the

Framingham Offspring Study. Prev Med 1987;16:235–51.

Brown CD, Higgins M, Donato KA, Rohde FC, Garrison R,

Obarzanek E, et al. Body mass index and the prevalence of

hypertension and dyslipidemia. Obes Res 2000;8:605–19.

Joint National Committee on prevention detection evaluation

and treatment of high blood pressure. The sixth report of the

Joint National Committee on prevention, detection,

evaluation, and treatment of high blood pressure. Arch

Intern Med 1997;157:227–34.

Hanson L. Primary prevention of coronary heart disease:

what is left to be done? Medicographia 1998;20:183–6.

Ghaffar A, Reddy KS, Singhi M. Burden of noncommunicable diseases in South Asia. BMJ 2004;328:811–5.

Khan H, Hafizullah M, Ihtesham-ul-Haq. A hospital based

study on frequency of risk factors of coronary artery disease

in Peshawar. J Postgrad Med Inst 2005;19:270–5.

Hassan M, Awan ZA, Gul AM, Sahibzada WA, Hafizullah

M. Prevalence of coronary artery disease in rural areas of

Peshawar. J Postgrad Med Inst 2005;19:14–22.

Eisenstein EL, Shaw LK, Nelson CL, Anstrom KJ, Hakim Z,

Mark DB. Obesity and long-term clinical and economic

outcomes in coronary artery disease patients. Obes Res


Ruthan GH, Kuller LH. Morbidity associated with diastolic

hypertension and isolated systolic hypertension among men

screened for multiple risk factors intervention trial.

Circulation 1998;77:504–14.

J Ayub Med Coll Abbottabad 2010;22(2) 133

Contaldo F, Pasanisi F, Finelli C, de Simone G. Obesity,

heart failure and sudden death. Nutr Metab Cardiovasc Dis


Lauer MS, Anderson KM, Levy D. Separate and joint

influences of obesity and mild hypertension on left

ventricular mass and geometry. J Am Coll Cardiol


Nishtar S. Prevention of coronary artery diseases in South

Asia. Lancet 2002;360:1015–8.

Bhopal R. Epidemic of cardiovascular disease in South

Asians. Prevention must start in childhood. BMJ


Sjostrom CD, Lissner L, Wedel H, Sjostrom L. Reduction in

incidence of diabetes, hypertension and lipid disturbances

after intentional weight loss induced by bariatric surgery: the

SOS Intervention Study. Obes Res 1999;7:477–84.



Most read articles by the same author(s)

<< < 1 2 3