RELATIONSHIP OF GLYCAEMIA AND TRIGLYCERIDES WITH BMI IN DIABETIC PATIENTS
AbstractBackground: Diabetes mellitus (DM) is a metabolic disorder characterised by chronichyperglycaemia with disturbances in carbohydrate, fat and protein metabolism arising from defectin insulin secretion or action or both. The clinical guidelines recommend measurement of BMI as“vital signs” for evaluating the obese and diabetic patients. Methods: This study was carried outon 160 diabetics, which were divided on the basis of BMI into obese (120) and non-obese (40)diabetics from Peshawar district. All patients had their triglycerides and glucose checked afterover night fast. Results: The serum triglyceride in diabetics having BMI >30 (obese) wasincreased as compared to patients having BMI <30 (non-obese). The comparison of serum glucoselevel in obese diabetics was found to be significantly raised as compared to non-obese diabetics.Conclusions and Recommendations: It was concluded that dyslipidemia is common in alldiabetics. The abnormal triglyceride level can improve with good glycaemic control, but do notreach the normal state. Good glycaemic control, Reducing BMI, periodic checkups of lipids andblood glucose are recommended for all diabetics in order to avoid complications.Keywords: Triglyceride, BMI, obese, non-obese, type 2 diabetics
Marshall WJ. Lipids and lipoproteins. Clinical chemistry, 4th
Ed. London: Mosby book; 2000. p. 231–5.
Mayne, PD: Hyperglycemia and diabetes mellitus. In: Zilva’s
clinical chemistry in diagnosis and treatment. 6th Ed. Glasgow:
Bath Press Color Books: 1994.p 206–9.
Roldofo V. Detecting undiagnosed type 2 diabetes: family
history as a risk factor and screening tool. J Diabetes Sci
Dedoussis, GV, Kaliora AC, Panagiotakos DB. Genes diet and
type-2 diabetes: areview. Diabetes care 2007;4(1): 13–24.
Betterridge DJ. Diabetic dyslipidemia. Diabetes Care
Malik MS, Raza SN, Hussain. Diabetic control and serum
lipids in diabetics attending a Pakistani Hospital. Pak J Med Sci
Chetlin RD, Brinkley JL, Spatafore AJ, Gilleland DL, Wheele
SD. Assessing Quality-of-life, Roles, And BMI in Type 2
Diabetes Patients Participating In Supervised Exercise. Med
Sci Sports Exerc 2009;41(5):440.
Oh Rc, Brain JL. Management of Hypertriglyceridemia. Am
Fam Physician 2007;75:1365–71.
Bray GA, Gray DS. Obesity, Part I, Pathogenesis. West J Med
J Ayub Med Coll Abbottabad 2010;22(2)
Jafar TH, Chaturvedi N, Pappas G. Prevalence of overweight
and obesity and their association with hypertension and
diabetes mellitus in an Indo-Asian population. CMAJ
Flegal KM, Carroll MD, Kuczmarski RJ, Johnson CL.
Overweight and obesity in the United States: prevalence and
trends, 1960–94. Int J Obes Relat Metab Disord
Bland M. Introduction to medical statistics 1st Ed. London:
Amer W, Zafar S, Majrooh A. Comparison of dyslipidemias in
controlled and uncontrolled type 2 diabetics. Ann King Edward
Med Coll 2004;10(2):158–60.
Garg A, Grundy SM. Gemfibrozil alone and in combination
with lovastatin for treatment of hypertriglyceridemia in
NIDDM. Diabetes 1989;38:364–72.
Arbeeny CM, Nordin C, Edelstein D, Stran N, Gibbons N,
Eder HA. Hyperlipoproteinimia in spontaneously diabetic
guinea pigs. Metabolism 1989;38:895–900.
Haider Z, Usma S, Jabeen M, Bano KA, Obaidullah S, Fayyaz
A. Profiles of hyperlipidemia in various patient groups and
controls. Pak J Med Res 1981;20(3):63–6.
Lampman RM, Schteingart DE. Effects of exercise training on
glucose control, lipid metabolism, and insulin sensitivity in
hypertriglyceridemia and non-insulin dependent diabetes
mellitus. Med Sci Sports Exerc 1991;23(6):703–12.