• Shamsunnisa Sadia
  • Fareesa Waqar
  • Tasneem Akhtar
  • Sadia Sultana


Background: Ovulatory dysfunction is a group of disorders with variable clinical presentationsoccasionally having serious long-term adverse effects. It accounts for 30% of female fertility problems.Evidence suggests an association between an individual’s weight and disorders of ovulation. Theobjective of our study was to describe the clinical and hormonal profile of subfertile women withovulatory dysfunction in relation to their body mass index (BMI). Methods: This prospective,descriptive study was carried out in Mother and Child Health Centre, PIMS, Islamabad and Railwayhospital, Rawalpindi from April 2001 to March 2007. One hundred & thirty eight infertile patients withovulatory dysfunction were included. The clinical data including BMI of each patient was recorded inaddition to reports of investigations comprised of cervical smear, pelvic ultrasound and hormonalprofile. Results: Primary infertility was found in 61% while secondary in 39% of the patients. Themean age was 29 years and mean duration of infertility was 6 years. Menstrual pattern was normal in56.5%. BMI was normal in 30.4% while most patients were overweight and obese. Prolonged cycles,history of systemic endocrine disorders, abnormal vaginal discharge, hirsutism, polycystic ovarianmorphology and hormonal abnormalities were more frequent in patients with increased BMI. Duringthe study period, 21.7% of the women conceived. Conclusion: Infertile patients with ovulatorydysfunction present more frequently with primary infertility. They usually have higher than requiredBMI. Oligomenorrhoea amenorrhoea, hirsutism and hormonal abnormalities are more frequent inoverweight than infertile patients with ovulatory dysfunction having a normal BMI.Keywords: Infertility, Ovulatory Dysfunction, Clinical Characteristics, Body mass index, BMI


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