MATERNAL SERUM LEVELS OF ADIPONECTIN IN PREECLAMPSIA
AbstractBackground: The results of the serum levels of adiponectin in preeclamptic patients areconflicting. Objective: The aim of the present study was to assess serum levels of adiponectin inwomen with preeclampsia compared with healthy pregnant women. Methods: A cross-sectionalstudy was designed. The case group consisted of women with preeclampsia (n=30). The controlgroup consisted of 30 matched normal pregnant women. Serum levels of adiponectin wereassessed using enzyme-linked immunosorbent assay method. Results: Serum levels of adiponectinwere significantly higher in the preeclamptic group than those in the normal control group. In thepreeclamptic patients serum levels of adiponectin showed a significant negative correlation withbody mass index while no correlation was found in the normal pregnant women. In women withpreeclampsia, levels of adiponectin were decreased significantly in the overweight womencompared with normal weight women, while in the control group no significant difference wasobserved. Conclusion: In conclusion, elevation of adiponectin levels might be a physiologicalfeedback response to minimize endothelial dysfunction in preeclamptic patients.Keywords: Serum, Adiponectin, Preeclampsia, Pregnancy, BMI, ELISA.
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