• Muhammad Ayub Musani
  • Itrat Jawed
  • Saleem Marfani
  • Yousuf Khambaty
  • M. Jalisi
  • Shahbaz Ali Khan


Background: Oral cancer varies globally and regionally, and is closely linked with geographical,social, economical, biological, ethnic, dietary and environmental factors. In western countries itaccounts for about 2–5% while in the south-east Asia for about 40% of all cancers. In Pakistan it issecond commonest tumour after bronchogenic carcinoma in males and breast carcinoma infemales. The objectives of this study were to find out the pattern of carcinoma cheek in our region,its etiological associations, management and prognosis. This study was conducted in theOtolaryngology and Head and Neck Surgery Department of Civil Hospital, Karachi from April 1995to December 1998. It was prospective study. Methods: Forty-five cases of primary carcinoma cheekwere diagnosed and investigations including OPG and CT scan were carried out along with otherrequired investigations to evaluate the extension of tumour, bony erosion and metastasis. TNMstaging was done. All patients were treated surgically, sent for post-operative radiotherapy orchemoradiation and followed up for 3 years. Result: Among 45 cases of oral cancer, 28 werefemales and 17 were males. Common presenting symptom was growth or ulcer. It was morecommon in 41–50 years of age. Squamous cell carcinoma (SCC) was found in 95.5% of the cases.Most of the patients 31 (68%) were in T4 stage. Surgical excision was done in all cases withreconstructuion in 23 cases and neck dissection in 39 cases. In the follow up for 3 years, 30 patientremained disease free. Conclusion: Carcinoma cheek is a common entity in our region and now it isseen in relatively younger patients. Oral cancer is a self preventable disease. What is required is todevelop awareness of oral hygiene and discourage the habit of social carcinogens use. Earlydiagnosis and treatment offers better chance of cure whereas advance disease has a poor prognosis.Keywords: Oral cavity squamous cell carcinoma (OSCC), supraomohyoid neck dissection.


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