SYNOVIAL SARCOMA OF THE LARYNX
AbstractSynovial sarcoma is a mesenchymal spindle cell tumour that displays variable epithelial differentiation. It most commonly occurs in lower extremities. Head and neck is a rare site for synovial sarcoma accounting for less than 10%. Larynx is an extremely rare site and only 16 cases with laryngeal location have been reported. Immunohistochemistry is important for correct diagnosis. Surgical excision of the tumour with clear margins and local radiotherapy is effective in local control. Chemotherapy is indicated in the presence of distant metastasis. Case of a 16 years old female is presented with hoarseness of voice and mass in supraglottic region. Lateral pharangotomy and excision of mass revealed synovial sarcoma. She had been treated with adjuvant radiotherapy in September 2012. She was fine and coming for regular follow up.
Weiss SW. Goldblum JR. Malignant soft tissue tumours of uncertain type.In: Enzinger and Weiss’s Soft Tissue tumors.4thed. St Louis Mo Mosby 2001. Dei Tos AP, Dal Cin P, Sciot R, Furlanetto A, Da Mosto MC, Giannini C, et al. Synovial sarcoma of the larynx and hypopharynx. Ann Otol Rhinol Laryngol 1998;107(12):1080–5.
Skytting B. Synovial sarcoma. A Scandinavian sarcoma Group Project. Acta Orthop Scand Suppl 2000;291:1–28.
Boniver V, Moreao P, Lefebvre P. Synovial Sarcoma of Larynx: Case report and literature review. B–ENT 2005;1(1):47–51.
Garensteina, Neel HB 3rd, Weiland LH, Devine KD. Sarcomas of the larynx. Arch Otolaryngol 1980;106(1):8–12.
Morland B, Cox G, Randall C, Ramsay A, Radford M. Synovial sarcoma of the larynx in a child;case report and histological appreances. Med Pediatr Oncol 1994;23(1):64–8.
Bilgic B, Mete O, Oztürk SA, Demiryont M, Keles N, Basaran M. Synovial sarcoma :a rare tumor of Larynx. Pathol Oncol Res 2003;9(4):242–5.
Ferlito A, Caruso G. Endolaryngeal synovial sarcoma. An update on diagnosis and treatment. ORL J Otorhinolaryngol Relat Spec 1991;53(2):116–9.
Gatti WM, Strom CG, Orfei E. Synovial sarcoma of laryngopharynx. Arch Otolaryngol 1975;101(10):633–6.
Geahchan NE, Lambert J, Micheau C, Richard JM. [Malignant synovioma of the larynx] .Ann Otolaryngol Chir Cervicofac 1983;100(1):61–5.
Kitsmaniuk ZD, Volkon IuM, Demochko VB, Ivanov AD. [Synovial sarcoma of the larynx]. Vestn Otorinolaringol 1985;(2):61–2.
Capelli M, Bertino G, Morbini P, Proh M, Falco CE, Benazzo M. Co2 Lazer in the treatment of Laryngeal Synovial Sarcoma: A Clinical Case .Tumori 2007;93(3):296–9.
Miller LH, Santaella-Latimer L, Miller T. Synovial sarcoma of the larynx. Trans Sect Otolaryngol Am Acad Ophtalmol Otolaryngol 1975;80(5):448–51.
Pruszczynski M, Manni JJ, Smedts F. Endolaryngeal synovial sarcoma: Case report with immunohistochemical studies. Head Neck 1994;11(1):76–80.
Quinn HJ Jr. Synivial sarcoma of the larynx treated by partial laryngectomy. laryngoscope 1984;94(9):1158–61.
Al-Nemer A, EI-Shawarby MA. Laryngeal synovial sarcoma: Case report and Literature review. Gulf J Oncolog 2011;(9):52–6.
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