COMPARISON OF FREQUENCY OF HEPATITIS B AND HEPATITIS C IN PREGNANT WOMEN IN URBAN AND RURAL AREA OF DISTRICT SWAT

Authors

  • Sania Tanweer Khattak
  • Mumtaz Ali Marwat
  • Imran ud Din Khattak
  • Taj Muhammad Khan
  • Tabassum Naheed

Abstract

Objectives: This retrospective analytical study was carried out to observe the frequency of Hepatitis Band Hepatitis C among the pregnant women of Swat. Methods: The study was carried out fromJanuary 2008 to December 2008. It was a retrospective study based on review of records of pregnantwomen admitted to Labour Room of Obstetrics/Gynaecology Unit, Saidu Teaching Hospital, Swat.Patients were screened for Hepatitis B and C by Immuno Chromatographic Technique (ICT) device.The findings were recorded on proforma and analysed. Those found positive on screening test wereconfirmed by ELISA. Results: Total number of patients screened was 5607. The frequency of HepatitisB and C (Combined) was 223 (3.98%), out of which 77 (1.37%) were HBsAg positive, 141 (2.52%)were anti HCV positive and 5 (0.09%) were both HBsAg and anti HCV positive. The frequency ofHepatitis B amongst age groups 14–19 , 20–29, 30–39 and 40–49 years were 2/77, 33/77, 40/77, and2/77) respectively. The frequency of Hepatitis C amongst age groups 14–19, 20–29,30–39 and 40–49years was 4/141, 59/141, 67/141 and 11/141 respectively. The frequency of Hepatitis B and C inmultigravida was 41/77, 67/141, in grand multigravida it was 20/77, 43/141 and in primigravida it was16/77, 31/141 respectively. The frequency of Hepatitis B and Hepatitis C amongst urban and ruralpopulation was 32 (39.02%) and 50 (60.98%); and 40 (27.40%) and 106 (72.60%) respectively. Thefrequency of Hepatitis B and C (Combined) in urban, rural population were 72 (31.58 %) and 156(68.15 %) respectively. Conclusion: HBsAg and HCV was common infections in pregnant women ofSwat. Therefore, every pregnant woman undergoing delivery and/or any other surgical procedure mustbe screened for Hepatitis B and Hepatitis C.Keywords: Screening, Hepatitis, Hepatitis B, Hepatitis C, HBsAg, HCV, Pregnancy, Swat

References

Ahmad I, Khan SB, Rahman HU, Khan MH, Anwar S.

Frequency of Hepatitis B and Hepatitis C among cataract

patients. Gomal J Med Sci 2006;4:61–4.

Chaudhary IA, Khan SA, Sami Ullah. Should we do Hepatitis

B and C screening on each patient before surgery analysis of

-cases. Pak J Med Sci 2005;21:278–80.

Khokar N, Gill ML, Malik GJ. General seroprevalence of

Hepatitis B and C virus infection in population. J Coll Phys

Surg Pak 2004;14(9):534–6.

Muhammd J, Hussain M, Khan MA. Frequency of Hepatits-B

and Hepatitis C infection in thalassaemic children. Pak Paed J

;27(4):161–4.

Ahmad K. Hepatitis B in: Viral Hepatitis: An overview:

proceedings of seminar, AFIP Rawalpindi, Pakistan 1998;16–19.

Schiff E. Hepatitis Central, Current information on Hepatitis C

and treatment for medical profession, Uni Miami 2002;1–2.

Hepatitis C, Fact Sheet No 204 Geneva, World Health

Organization. 2000.

Yusaf A, Muhammad A, Ishaq M. Can we afford to operate on

patient with HBsAg screening. J Coll Physicians Surg Pak

;9:98–100.

Malik IA, Legters LJ, Luqman M. The serological markers of

Hepatitis-A and B in health population in northern Pakistan. J

Pak Med Assoc 1988;38:67–72.

Umar M, Bushra HT, Shuaib A. Spectrum of chronic liver

disease due to HCV infection. J Coll Physicians Surg Pak

;6:234–7.

Wasim J, Nadim J, Javed Y. Hepatitis B and C prevalence and

risk factors associated with seropositivity among children in

Karachi, Pakistan. BMC Infect Diseas 2006;6:101–3.

Parker SP, Khan HI, Cubitt WD. Detection of antibodies to

Hepatitis C virus in dried blood spot samples from mothers and

their offspring in Lahore, Pakistan. J Clin Microbiol

;37:2061–3.

Thorburn D, Roy K, Cameron SO. Risk of hepatits-C virus

transmission from patients to surgeons. Gut 2003;52:1333–8.

Ahmad J, Taj AS, Rahim A, Shah A, Rehman M. Frequency

of Hepatitis B and Hepatitis C in healthy blood donor of

NWFP. J Postgrad Med Inst 2004;18:343–52.

Batool A, Bano KA, Khan MUL, Hussain R. Antenatal

screening of women for Hepatitis B and C in an out patient

department. J Dow Univers Health Sci 2008;2:32–35.

Bukhari SM, Khatoon N, Iqbal A. Prevalence of Hepatitis B

antigenaemia in Mayo Hospital Lahore. Biomedica

;15:88–91.

Sultana N, Bari A, Qazalbash AA. Prevalence of Anti-HCV

antibodies in patients with liver disease and normal population.

Pak J Med Res 1999;49:15–7.

Tariq W, Hussain AB, Karamat KA, Ghani E, Hussain T,

Hussain S. Demographic aspects of Hepatitis C in northern

Pakistan. J Pak Med Assoc 1999;49:189–201.

Nelson PC. Liver disease: In ; handbook of Obstetric medicine.

nd Ed. London: Martin Dunitz; 2002. p.199–202.

Ohto H, Terazama S, Sasaki N. Transmission of Hepatitis C

virus from mother to infant. N Eng Mrd 1994;330:744–50.

Ni YH, Lin HL, Chen PJ, Hsu HY, Chen DS, Chang MH.

Temporal profile of Hepatitis C virus antibody and genome in

infants born to mother infected with hepatitis C virus but

without human immunodeficiency virus co- infection. J

Hepatol 1994;20:651–5.

Manzini P, Saracoo G, Cherchier A. Human

Immunodeficiency virus infection as risk factor for mother to

child virus transmission. Pew resistance of anti hepatitis virus

in children is associated with the mother anti Hepatitis C virus

immunobloting pattern. Hepatol 1995;21:328–32.

J Ayub Med Coll Abbottabad 2009;21(2)

http://www.ayubmed.edu.pk/JAMC/PAST/21-2/Sania.pdf 15

Ward C, Tudor WG, Lotzias T, Hargreaves S, Regan L, Foster

GR. Prevalence of Hepatitis C among pregnancy women

attending an inner London obstetric department. Uptake and

acceptability of named antenatal testing. Gut 2000;47:277–80.

Ilyas M, Hussain T, Tariq WUZ, Bhatti FA, Ahmad F.

Epidemiology of Hepatitis C virus infection in blood donor in

northern Pakistan. J Med Res C 2001;5:56–9.

Sypsa VE , Hadjipaschali E, Hatzakis A. Prevalence , risk

factors and evaluation of a screening strategy for Hepatitis C

& B virus infections in healthy company employees. Euro J

Epidemiol 2001;17:721–3.

Taguchi S, Nishioka K, Kawaguchi R, Nakao M, Watanabe I,

Migita T. Epidemiological study of Hepatitis B and C in

,336 patients operated at Hiroshima Prefectural Hospital

during the period from 1993 to 2000. Masui 2004;53:696–700.

Erden S, Buyukozturk S, Calangu S, Yilmaz G Palanduz S,

Badur S. Study of serological markers of Hepatitis B and C

virus in Istanbul, Turkey. Med Princ Pract 2003;12(3):184–8.

Masood Z, Javaid M, Khan RA, Rehman SU. Screening for

Hepatitis B and C a routine preoperative investigation. Pak J

Med Sci 2005; 21:455–9.

Ali SA, Shah FA, Ahmed K. Prevalence of Hepatitis B and C

virus in surgical patients. Pak J Surg 2007;23:109–12.

Awan SN, Nayyar S, Ashraf N. Obstetrics and perinatal out

come; Risk factors for Hepatitis B and C transmission.

Professional Med J 2006;13:511–6.

Ali HS, Memon MA. Prevalence of Hepatitis B infection in

pregnant women in a tertiary care hospital. Infect Dis J Pak

;2:35–8.

Asif SA, Iqbal R, Hussain H, Khan MH.Awareness of viral

hepatitis in ten villages of districts Nowshera. Gomal J Med Sci

;7:10–3.

Published

2009-06-01

Most read articles by the same author(s)