ANIRIDIA: A RARE MANIFESTATION OF CONGENITAL RUBELLA SYNDROME
Abstract
A foetus affected by a congenital rubella infection can develop congenital rubella syndrome (CRS). Aniridia is the absence of iris, rarely been described in literature in association with CRS, can easily be overlooked, leading to complications e.g. glaucoma and blindness later in life. We report a case of a neonate with CRS and aniridia presenting at a tertiary care hospital.Keywords: Aniridia; Congenital; Rubella; Syndrome; Iris; HypoplasiaReferences
Kliegman R, Behrman RE, Nelson WE, editors. Nelson textbook of pediatrics. 20th ed. Phialdelphia, PA: Elsevier, 2016; p.1548–52.
Gregg NM. Congenital cataract following German measles in the mother. 1941. Epidemiol Infect 1991;107(1):iii–xiv.
WHO. Rubella vaccine: WHO position paper. Wkly Epidemiol Rec 2000:75:161–72.
Robertson SE, Featherstone DA, Gacic-Dobo M, Hersh BS. Rubella and congenital rubella syndrome: global update. Rev Panam Salud Publica 2003;14:306–15.
Vijayalakshmi P, Kakkar G, Samprathi A, Banushree R. Ocular manifestations of congenital rubella syndrome in a developing country. Indian J Ophthalmol 2002;50(4):307–11.
Vijayalakshmi P, Rajasundari TA, Prasad NM, Prakash SK, Narendran K, Ravindran M, et al. Prevalence of eye signs in congenital rubella syndrome in South India: a role for population screening. Br J Ophthalmol 2007;91(11):1467–70.
Gillies WE. Hypoplasia of the iris stroma in Gregg's syndrome unaccompanied by cataract but with deafness, rubella retinopathy and onset of glaucoma in adult or adolescent life. Aust J Ophthalmol 1980;8(2):189–92.
Wilson EM, Saunders R, Rupal T. Pediatric ophthalmology: current thought and a practical guide. Springer Science & Business Media; 2008;355–6.
Lang GK, Gareis O. Ophthalmology: a pocket textbook atlas. 2nd ed., rev. and enl. Stuttgart; New York: Thieme, 2007; p.607.
Ross M, Roy H. Aniridia: Background, Pathophysiology, Epidemiology. [Internet]. [cited 2016 Oct 4]. Available from: http://emedicine.medscape.com/article/1208379-overview
Brooks AM, Gillies WE. Congenital rubella syndrome. Br J Opthalmol 1994;78(1);79.
