• Inayat Ullah Khan
  • Muhammad Burhanuddin Janjua
  • Shumaila Hasan
  • Shahid Shah


Background: Postoperative wound infection also called as surgical site infection (SSI), is atrouble some complication of lumbar spine surgeries and they can be associated with seriousmorbidities, mortalities and increase resource utilization. With the improvement in diagnosticmodalities, proper surgical techniques, antibiotic therapy and postoperative care, infectiouscomplications can result in various compromises afterwards. The objective was to study therelation of surgical site infection in clean lumbar surgeries with the doses of antibiotics. ThisRetrospective study was conducted at Shifa International Hospital, from January 2006 to March2008. Methods: Hundred post operated cases of lumber disc prolapse, lumbar stenosis or bothstudied retrospectively by tracing their operated data from hospital record section for thedevelopment of surgical site infection (SSI). The patients were divided into three groupsdepending upon whether they received single, three or more than three doses of antibioticsrespectively. Complete data analyses and cross tabulation done with SPSS version 16. Result: Of100 cases, only 6% had superficial surgical site infection; only 1 case with co morbidity ofhypertension was detected. Twenty-one cases had single dose of antibiotic (Group-I), 59 cases had3 doses (Group-II) and 20 cases received multiple doses (Group-III). There was no infection inGroup-I. Only one patient in Group-II and 5 patients in Group-III developed superficial SSI.While 4 in Group-II, 3 in Group-III, and none of Group-I had >6 days length of stay (LOS).Conclusion The dose of antibiotic directly correlates with the surgical site infection in cleanlumbar surgeries. When compared with multiple doses of antibiotics a single preoperative shot ofantibiotic is equally effective for patients with SSI.Keywords: Lumber surgery, surgical site infection, wound infection


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