YIELD OF ABRAMS NEEDLE PLEURAL BIOPSY IN EXUDATIVE PLEURAL EFFUSION
AbstractBackground: Pleural effusion is the abnormal collection of fluid in the pleural space resulting fromexcessive fluid production or decreased absorption and it is one of the most common clinical conditionsthat we come across in pulmonology clinics and in hospitals. The objective of prospective study was toevaluate the diagnostic role of Abrams Needle Biopsy in Exudative Pleural Effusion Methods: Thestudy was performed at the Department of Pulmonology, Ayub Teaching Hospital, Abbottabad over aperiod of 1 year, i.e., January 2008 to December 2008. Sixty-three patients of either sex and all ageswith exudative pleural effusion, on whom Abrams Needle Biopsy was performed were included in thestudy. Minimum of four specimens from each patient were taken and histopathology done. Results:Out of 63 patients, histopathology revealed the cause in 60 (95%) cases. Tuberculosis, malignancy andrheumatoid pleurisy were confirmed in 34, 24, and 2 cases respectively. Specimens of 3 patients did notreveal any result and showed non-specific inflammation and were further investigated accordingly.Conclusion: The diagnostic yield of Biopsy was 95%. Pleural biopsy is still a reliable and valuableinvestigation in diagnosing pleural effusion, provided that adequate pleural specimen is taken.Keywords: Pleural biopsy, Exudative pleural effusion, malignant pleural effusion, Tuberculosis
Diaz-Guzman E, Dweik RA. Diagnosis and management of
pleural effusions: a practical approach. Compr
Marel M, Zrustova M, Stasny B, Light RW. The incidence of
pleural effusion in a well-defined region. Epidemiologic
study in central Bohemia. Chest 1993;104:1486–9.
Light RW, MacGregor MI, Luchsinger PC, Ball WC Jr.
Pleural effusion: The diagnostic separation of transudates and
exudates. Ann Intern Med 1972;77:507–13.
Noble J. Textbook of Primary Care Medicine. 3rd ed. St.
Louis, Mo: Mosby; 2001.p.725.
Heidari B, Bijani K, Eissazadeh M, Heidari P. Exudative
pleural effusion: effectiveness of pleural fluid analysis and
pleural biopsy. East Mediterr Health J. 2007;13:765–73.
Frank W. Current diagnostic approach to pleural effusion.
Khadadah ME, Muqim AT, Al-Mutairi AD, Nahar IK,
Sharma PN, Behbehani NH, et al. Closed percutaneous
pleural biopsy. A lost art in the new era. Saudi Med J
Chakrabarti B, Ryland I, Sheard J, Warburton CJ, Earis JE.
The role of Abrams percutaneous pleural biopsy in the
investigation of exudative pleural effusions. Chest.
Light RW, Erozan YS, Ball WC Jr. Cells in pleural fluid.
Their value in differential diagnosis. Arch Intern Med