PATTERN OF BREAST CANCER: EXPERIENCE AT LADY READING HOSPITAL, PESHAWAR
AbstractBackground: Breast Cancer is the commonest malignancy of females all over the world and secondleading cause of death due to cancer among females. The aim of this Descriptive study was to see thevarious features of breast cancer in order to know the pattern of disease in the recent time. The studywas conducted from Jan. 2007 to Dec. 2007 in Surgical C Unit, Postgraduate Medical Institute, LadyReading Hospital, Peshawar, Pakistan. Methods: Study included all patients presenting to andadmitted in Surgical C Unit LRH, with carcinoma of breast during the above mentioned period.Name, age, sex, other relevant data, history and examination findings and results of histopathologyand other investigations were recorded. Results: Total of 46 patients was included in the study, outof which there were 46 female and 1 male patients. Most common age group was 40–49 years with14 patients, followed by 50–59 years with 12 patients. Most common type of carcinoma wasinfiltrating ductal carcinoma with no specific features with 38 patients. Other types included 2infiltrating ductal carcinomas of papillary type, 1 mucinous type and 1 medullary type; 3 invasivelobular carcinomas, and 1 mixed lobular and ductal carcinoma. The disease was left sided in 24cases, right sided in 20 cases while it was bilateral in 2 cases. Upper outer quadrant of the breast wasmost commonly involved (n=26). There were 2 cases of stage I, 16 stage II, 20 stage III and 08 casesof stage IV disease. There were 2 cases of grade I, 16 grade II, and 28 cases of grade III.Conclusion: Carcinoma breast is still a common problem presenting at a young to middle age groupwith invasive ductal carcinoma being the commonest variant with a high grade and a late stage ofpresentation due to lack of screening and awareness programs.Keywords: Breast carcinoma
Mahmood S, Rana TF, Ahmad M. Common determinants of
Ca Breast–a case control study in Lahore. Ann King Edward
Med Coll 2006;12:227–8.
Hunter CP. Epidemiology, stage at diagnosis, and tumor
biology of breast carcinoma in multiracial and multiethnic
populations. Cancer. 2000;88(5 Suppl):1193–202.
Russel RCG, William NS, Bulstrode CJK. Bailey and Love’s
Short Practice of Surgery. 24th ed. London; Arrnold; 2004.
Cuschieri A, Steele RJC, Moossa AR. Essential Surgical
Practice.4th ed. New York: Oxford University Press; 2002.
Ahmed R, Shaikh H, Hasan S. Is carcinoma breast a different
disease in Pakistani population? J Pak Med Assoc 1997;47:114–6.
Sohail S, Alam SN. Breast cancer in Pakistan–awareness and
early detection. J Coll Physicians Surg Pak 2007;17:711–2.
Alahwal MS. HER-2 positivity and correlations with other
histopathologic features in Breast Cancer patients–hospital
basd study. J Pak Med Assoc 2006;56:65–8.
Aftab ML, Rashid A. A Clinico Pathological Study of
Carcinoma Breast. Pak J Health 1998;35(3-4):96–8.
Siddiqui M, Kayani N, Sulaiman S, Hussainy A, Shah S,
Muzaffar S. Breast carcinoma in Pakistani females: a
morphological study of 572 breast specimens. J Pak Med
Siddiqui K, Rasool MI. Pattern of Breast Diseases:
Preliminary Report of Breast Clinic. J Coll Physicians Surg
Baloch TA, Iqbal P. Breast carcinoma in Karachi Clinical &
Pathological Features. Med Channel 2006;12:47–8.
Batool M, Arian M, Gardezi J. An experience with breast
disease in a surgical unit of a teaching hospital of Lahore.
Aslam MN, Ansari AK, Siddique A, Imran M. Carcinoma
breast, late presentation-a big concern. Ann King Edward
Med Coll 2006;2:317–9.
Qureshi S, Ghazanfar S, Memon SA, Attaullah, Quraishy
MS, Sultan N. Five years experience of carcinoma breast. J
Surg Pak 2007;12:52–5.
Gilani GM, Kamal S, Akhter A S. A differential study of
Breast Cancer Patients in Punjab, Pakistan.J Pak Med Assoc
Kuraparthy S, Reddy KM, Yadagiri LA, Yutla M, Venkata
PB, Kadainti SV et al. Epidemiology and patterns of care for
invasive breast carcinoma at a community hospital in
Southern India. World J Surg Oncol 2007;5:56.
Klonoff-Cohen HS, Schaffroth LB, Edelstein SL, Molgaard
C, Saltzstein SL. Breast cancer histology in Caucasians,
African Americans, Hispanics, Asians, and Pacific Islanders.
Ethn Health. 1998;3:189–98.
Yip CH; Taib NA; Mohamed I. Epidemiology of breast
cancer in Malaysia. Asian Pac J Cancer Prev. 2006;7:369–74.
Arndt V, Stürmer T, Stegmaier C, Ziegler H, Dhom G,
Brenner H. Socio-demographic factors, health behavior and
late-stage diagnosis of breast cancer in Germany: a
population-based study. J Clin Epidemiol 2001;54:719–27.
Oluwole SF, Ali AO, Adu A, Blane BP, Barlow B, Oropeza
R, et al. Impact of a cancer screening program on breast
cancer stage at diagnosis in a medically underserved urban
community. J Am Coll Surg 2003;196:180–8.
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.