FREQUENCY OF ANTITOXOPLASMA ANTIBODIES IN PATIENTS WITH OCULAR PATHOLOGY
Abstract
Background: Toxoplasmosis is a worldwide disease caused by toxoplasma gondii. This disease is prevalent in many parts of the world including Pakistan. Besides other conditions,ocular diseases are also caused by it. Immune response is mounted against this protozoon in the form of antibodies which are detectable in patient’s serum. The present study estimated the seroprevalence of antitoxoplasma antibodies in patients with ocular diseases. Methods: One hundred patients of either sex and age were studied at the ophthalmology units of Jinnah Postgraduate Medical Centre and Lyari General Hospital Karachi. Antitoxoplasma antibodies, both immunoglobulin G and M (IgG & IgM) were detected in the sera of these patients by the recommended methods. Results: Seroprevalence of antitoxoplasma antibodies was highest (60%) in age groups 21 to 40 years. It was seen in either sex but was found to be more common in females. Conclusions: Further studies with improved diagnostic techniques on larger samples are needed to diagnose and treat toxoplasmosis in acute stage in order to minimize the deleterious effects it has on different tissues and organs of the body.Keywords: Antitoxoplasma, Antibodies, OcularReferences
Beattie CP. The Ecology of Toxoplasmosis. Ecology of Disease 1982;13-20.
Frenkel JK. Toxoplasmosis In: Strickland. Tropical Medicine. Philadelphia WB Saunders Company. 1984: 593-605.
Hogan MJ. Am Med Assoc Arch Ophthalmol 1956; 333-43.
Ahmed M, Hafiz A. Toxoplasmosis in children with congenital anomalies. Clin Ophthalmology 1989;5:142-5.
Frenkel JK. Pathogenesis, diagnosis and treatment of human toxoplasmosis. Jour Am Med Assoc 1949;140:369-77.
Dutton GN. The Causes of tissue damage in toxoplasmic retinochoroiditis. Clin Ophthal-mology 1989;5:142-5.
Beneson MW, Takafuji ET, Lemon SM, Greenup RL, Sulzer AJ. Oocyst- transmitted toxoplasmosis associated with ingestion of contaminated water. New Engl J Med 1982; 307(11):660-6.
Ahmed M, Hafiz A. Surveillance of toxoplasmosis in different groups. J Pak Med Assoc 1989;39:183-6.
Hogan MJ, Kimura SJ, O’Connor G. Ocular Toxoplasmosis. Arch Ophthalmol 1969;72:592-600.
W.H.O.Toxoplasmosis. Report of a W.H.O. meeting of investigators. W.H.O. Tech Rep Ser.1969; 431:5-3.
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