ULTRASOUND -A USEFUL COMPLEMENTARY TOOL TO MAMMOGRAPHY IN ASSESSMENT OF SYMPTOMATIC BREAST DISEASES
AbstractBackground: Breast cancer is the most common female malignancy worldwide. Pakistan has the highest incidence rate of breast cancer than any other Asian population. The purpose of the study was to evaluate the worth of sono-mammography in diagnosis of symptomatic breast diseases by comparing it with mammogram. Methods: In this cross-sectional validation study, 45 subjects with mean age of 45±12.07 were included. Majority of the patients presented with complaint of breast lump. After complete history and clinical examination, all the patients had high resolution ultrasound of bilateral breasts and axilla followed by bilateral mammography. Histopathology was taken as gold standard in this study. The exclusion criteria were pregnancy and patients having direct clinical signs of breast malignancy. Results: Based on histopathology, out of 45 patients with breast symptoms, 12 patients had benign lesions, whereas 32 patients were diagnosed as the cases of breast cancers. Finally one patient did not have biopsy proven final diagnosis. Sensitivity and specificity of ultrasound were calculated to be 100% and 67% as compared to sensitivity and specificity of 90.6% and 91.7% for that of mammography. Conclusions: Ultrasound is a useful complementary tool to mammography in assessment of symptomatic breast diseases since it helps in characterization and localization of breast lesions seen on mammogram and it is not limited by dense breasts. Also it should be the considered as initial imaging technique for assessment of palpable breast lumps.Keywords: Breast cancer, Mammogram, Ultrasound.
Mahmood S, Rana TF, Ahmad M. Common determinants of Ca Breast-a case control study in Lahore. Ann King Edward Med Coll 2006;12:227–8.
Mark D Pegram, Dennis A Casciato. Breast cancer. Manual of clinical oncology 6th edition p. 238–40.
Tabar L, Pentek Z, Dean PB. The diagnostic and therapeutic value of breast cyst puncture and pneumocystography. Radiology 1981;141(3):659–63.
Dr. Col. CS Pant. Introduction. Atlas of Breast Imaging. 2002:1-9.
Baker LH. Breast cancer detection Demonstration projects: five year summary reports. Cancer 1982;32(4):194–225.
Shapiro S, Veniet W, Strax P, Veniet L. Periodic screening for- breast cancer: the Health Insurance Plan Project and Its .Sequalae, 1963–86. Baltimore, MD: The Johnis Hopkins University; 1988.
Shapiro S, Venet W, Strax P, Venet L, Roeser R. Ten-to fourteen-year effect of screening of breast cancer mortality. J Natl Cancer Inst 1982;69(2):349–55.
Jackson VP. The current role of ultrasonography in breast imaging. Radiol Clin North Am 1995;33(6):1161–70.
Venta LA, Dudiak CM, Salomon CG, Flisak ME. Sonogarphic evaluation of the breast. Radiographics 1994;14(1):29–50