PATTERN OF CARCINOMA OF ORAL CAVITY REPORTING AT DENTAL DEPARTMENT OF AYUB MEDICAL COLLEGE

Authors

  • Abdul Wahid
  • Sajjad Ahmad
  • Mohammad Sajjad

Abstract

Background: Carcinoma of oral cavity is amongst the first ten commonest malignancies in Pakistan. Districts of Hazara (NWFP) and Northern Areas of Pakistan are among the high risk areas. Here we present a report of oral cancers received in this center over a period of 10 years. Methods: This clinicopathological study consists of cases of carcinoma of oral cavity presenting to dentistry department of Ayub Medical College Abbottabad during 1993-2003. All cases were clinically examined and provisionally diagnosed. Biopsy was taken from all the lesions and the tissues submitted to histopathology department of Ayub Medical College. Results: There were 50 carcinoma cases in the study, including 30 (60%) males and 20 (40%) females. Among these, 47 (94 %) were diagnosed as squamous cell carcinomas, that consisted 30 (63.82 %) males and 17 (36.17%) females. The other 6 % lesions were histologically diagnosed as malignant melanoma, adenocarcinoma and acinar cell carcinoma. The age of squamous cell carcinoma cases was 41-71 years. The maximum number of squamous cell carcinomas (34%) effected buccal mucosa. The other common sites were lip (26%), tongue (21%) and gums (19%). Conclusion: The results of this study are comparable with other such studies done in Pakistan and else where in  the world  showing  commonality of  factors associated with the development of the disease in this region of the country, which  necessitates a detailed prospective study.Keywords: Oral carcinoma, Squamous cell carcinoma, smokeless tobacco

References

Pakistan Medical Research Council cancer study group. Multicentre study of Malignant tumours. PMRC Monograph No.6, Karachi;1982.

WHO study group report on control of oral cancer in developing countries. Bull. WHO 1982;6:817-30.

WHO study Group Report on smokeless Tobacco control. WHO, Geneva;1987

Mehta FS, Aghi MB, Gupta PC, Pindborg JJ. An intervention study of oral cancer and pre-cancer in rural Indian population. Bull.WHO 1982;60:441-6

Jafarey NA, Zaidi SHM. Cancer in Pakistan. J Pak Med Assoc 1987;37:178-83.

Hirsch JM, Johansson SL, Vahl NE. Inhibition of Herpes simplex virus replication by tobacco extracts. Cancer Res 1984;44:1991-7.

ScullyC, Maitland NJ, Cox MF. Human papillomavirus DNA and oral mucas. Lancet 1987;21:336.

IARC. Tobacco habits other than smoking: IARC Monographs on evaluation of the carcinogenic risk of chemical to human 37 Layon. IARC;1985.

Flaitz CM, Nichols CM, Alder-storthz K, Hicks MJ.Intra oral squamous cell carcinoma in human immunodeficiency virus infection. Oral Surg Oral Med Oral Pathol;1996;80:55-62.

Walsh PM, Epstein JB. The oral effects of smokeless tobacco. J Can Dent Assoc 2000;66:22-5.

Lewin F, Norell SE, Johansson H. Oral snuff, smoking habits and alcohol consumption in relation to oral cancer in a Swedish case –control study. Int J Cancer 1998;77:341-6.

Krolls SO, Hoffman S. Squamous cell carcinoma of the oral soft tissues: a statistical analysis of 14,253 cases by age, sex and race of patients. J Am Dent Assoc 1976;92:571-5.

Downloads

Most read articles by the same author(s)

<< < 1 2