MICROALBUMINURIA: ASSOCIATION WITH ISCHAEMIC HEART DISEASE IN NON-DIABETICS
AbstractBackground: In view of the high morbidity and mortality associated with ischemic heart disease(IHD), the estimation of individual cardiovascular risk over and above the assessment of classicrisk factors, such as age, hypercholesterolemia and hypertension, is an important prerequisite forfocusing preventive measures and therapeutic measures. Microalbuminuria (MA) as a marker ofIHD in nondiabetics is currently under international debate. The present descriptive studyundertaken at Combined Military Hospital, Lahore was aimed to determine the frequency of MAin nondiabetic IHD patients. Methods: One hundred consecutive non diabetic patients with IHD(73 males, 27 females). Patients showing clinical albumiuria and with other causes of proteinuriawere excluded. Urinary albumin in first morning sample was estimated by immunoturbidimetrymethod. Albumin to creatinine ratio (ACR) was calculated as mg/g. Results: The frequency ofMA ( ACR > 30 mg/g) was 37% in patients. Frequency was highest in older age bracket for bothgenders. The mean ACR was 131.8±66.2 mg/g. Significant difference was observed in mean MAlevel among different age groups. Conclusion: MA is common in nondiabetics patients with IHD.The mean level of MA was higher in older patients.Key Words: Ischemic heart disease, nondiabetics, microalbuminuria, cardiovascular risk.
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