FREQUENCY OF PRIMARY SOLID MALIGNANT NEOPLASMS IN BOTH SEXES, AS SEEN IN OUR PRACTICE

Authors

  • Zubair Ahmad
  • Najamul Sahar Azad
  • Nausheen Yaqoob
  • Akhtar Husain
  • Aamir Ahsan
  • Ambreen Nasir Khan
  • Rashida Ahmed
  • Naila Kayani
  • Shahid Pervez
  • Sheema H. Hassan

Abstract

Background: To determine the frequency of various histologic types of primary solid malignant
neoplasms in males and females, in our practice, in a large series of surgical biopsies. Methods : A
retrospective study of 20,000 consecutive surgical biopsies in the section of Histopathology, Aga
Khan University Hospital (AKU), Karachi, in 2004. Results: Squamous cell carcinoma of oral
cavity was the commonest malignant neoplasm in males followed by diffuse Large B cell,
Non-Hodgkin's lymphoma and Prostatic adenocarcinoma. In females, infiltrating Ductal
carcinoma of the breast was overwhelmingly the commonest malignant neoplasm followed by
Squamous cell carcinoma of the oral cavity and esophagus. Conclusion: Out of 20,000 biopsies,
there were 4616 (23.08%) malignant neoplsms. Carcinoma of oral cavity is very common in our
population in both sexes.
Key Words: Malignant Neoplasm, Male, Female, Primary

References

Annual cancer registry report -2004. Shoukat Khanum Cancer

Hospital & Research Center. p 3.

Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world

cancer burden. Globocan 2000. Int J Cancer 2001;94(2):153-

Straus DJ, Filippa DA, Lieberman PH, Koziner B, Thaler

HT, Clarkson BD. The non-Hodgkin's lymphomas. I.A

retrospective clinical and pathologic analysis of 499 cases

diagnosed between 1958 and 1969. Cancer 1983;51(1):101-9.

Nelson WG, De Marzo AM, Isaacs WB. Prostate cancer:

mechanism of disease. N Engl J Med 2003;349(4):366-81.

Richardson GE, Johnson B E. The biology of lung cancer.

Semin Oncol. 1993;20(2):105-27.

Ferlay J, Bray F, Pisani P, Parkin DM, eds. Alobocan 2000:

Cancer incidence, mortality and prevalence worldwide. Lyon,

France: IARC Press 2001.

Lee SS, Ro JY, Luna MA, Batsakis JG. Squamous cell

carcinoma of the larynx in young adults. Semin diagn Pathol

; 4(2):150-52.

Voigt LF, Weiss NS. Epidemiology of endometrial cancer.

Cancer Treat Res 1989;49:1 -21.

Cannistra SA, Niloff JM. Cancer of the uterine cervix. N

Engl JMed 1996;334(16):1030-38.

Boyle P, Zaridze DG, Smans M. Descriptive epidemiology of

colorectal cancer. Int J cancer. 1985;36(1): 9-18.

Yang PC, Davis S. Incidence of cancer of the esophagus in

the US by histologic type. Cancer. 1988;61(3):612-17.

Correa P. The epidemiology of gastric cancer. World J Surg

;15:228-34.

Devesa SS, Blot WJ, Fraumeni JF Jr. Changing patterns in

the incidence of esophageal and gastric carcinoma in the

United States. Cancer. 1998;83(10):2049-53.

Noguchi Y, Yoshikawa T, Tsuburaya A, Motohashi H,

Karpeh MS, Brennan MF. Is gastric carcinoma different

between Japan and the United States? Cancer.

;89(11):2237-46.

EL-Serag HB, Mason AC. Rising incidence of hepatocellular

carcinoma in the United States. N Eng J Med. 1999;

(10):745-50.

Carriaga MT, Henson DE. Liver, gall bladder, extrahepatic

bile ducts and pancreas. Cancer. 1995;75(1 Suppl):175-90.

Schlumberger MJ. Papillary and follicular thyroid carcinoma.

N Engl J Med. 1998;338(5):297-306.

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Published

2007-03-01

How to Cite

1.
Ahmad Z, Azad NS, Yaqoob N, Husain A, Ahsan A, Khan AN, et al. FREQUENCY OF PRIMARY SOLID MALIGNANT NEOPLASMS IN BOTH SEXES, AS SEEN IN OUR PRACTICE. J Ayub Med Coll Abbottabad [Internet]. 2007 Mar. 1 [cited 2025 Jul. 6];19(1):53-5. Available from: https://jamc.ayubmed.edu.pk/index.php/jamc/article/view/4292

Issue

Vol. 19 No. 1 (2007): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

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