GASTROGRAFFIN USE IN DISTAL INTESTINAL OBSTRUCTION SYNDROME OF CYSTIC FIBROSIS
AbstractBackground: Meconium ileus equivalent or the Distal Intestinal Obstruction Syndrome (DIOS) isan entity that is frequently seen in patients with cystic fibrosis (CF). In the gastrointestinal tractcystic fibrosis may produces symptoms of malabsorption and constipation. The latter may beassociated with complications such as impaction and intestinal perforation. Meconium ileus andDIOS are an emergency and requires to be treated aggressively to ensure that consequences suchas perforation do not occur. Method: Traditional modes of management of DIOS have includedthe use of laxatives, Acetylcysteine and Gastrograffin enemas. We are describing the use of oralgastrograffin in our patient seen at the Aga Khan University Hospital where small bowelobstruction was refractory to treatment. Oral gastrograffin was used once diluted in 4 times thevolume of water or fruit juice with half doses given on day 2 and 3. Results: Oral gastrograffinuse was followed by relief of obstruction in this patient. Conclusion: Gastrograffin use orally orrectally may be helpful in the treatment of refractions distal intestinal obstruction syndrome incystic fibrosis.Keyword: Gastrograffin, Intestinal, Syndrome, Cystic fibrosis
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