C REACTIVE PROTEIN LEVELS AS A MARKER OF CORONARY HEART DISEASE IN MIDDLE AGED INDIVIDUALS

Authors

  • Nadia Haleem Lecturer,Bio Chemistry, Ayub Medical College Abbottabad
  • Zahid Irfan Marwat Bio Chemistry Ayub Medical College Abbottabad
  • Shazia Tauqeer Physiology Ayub Medical College Abbottabad
  • Sarwat Abbasi Bio Chemistry Ayub Medical College Abbottabad

Abstract

Background: coronary heart disease is multifactorial inflammatory process which involves the accumulation of lipid macrophages and intimal plaques in smooth muscle cell in large and medium sized arteries. C reactive protein (CRP) which is an inflammatory marker is considered as global risk assessment for coronary heart disease. The objective of study is to determine the CRP level as risk marker in coronary heart disease in middle aged individuals. Methods: This cross sectional study was conducted in Hayatabad medical complex Peshawar and Rehman Medical Institute Peshawar. On the basis of predesigned questionnaire, 100 middle aged individuals of age 40-60 years and 50 normal subjects of same age were questioned by taking consent. Data was collected and analysed by SPSS-15. Results: It was founded that 74% of patients have higher values of CRP and 4% have high values of CRP in controls. The t-test applied at 95% confidence interval with mean difference of 22.096+2.36 of CHD individuals and 1.288±1.70 of control group. P-value was 0.001 which is found to be significant. Conclusion: It was observed that CRP has higher association with CHD.

Author Biographies

Nadia Haleem, Lecturer,Bio Chemistry, Ayub Medical College Abbottabad

Lecturer

Zahid Irfan Marwat, Bio Chemistry Ayub Medical College Abbottabad

Bio Chemistry

Shazia Tauqeer, Physiology Ayub Medical College Abbottabad

Physiology Deptt

Sarwat Abbasi, Bio Chemistry Ayub Medical College Abbottabad

Bio Chemistry

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Published

2016-03-10

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