• Saqib Malik ATH
  • Alia Pervez ATH
  • Zarnab Zainab ATH


Background: Cerebral infraction is one of the important causes of cerebrovascular accident. This study was conducted to see which risk factors are more prevalent in cerebral infraction. Methods: It is a hospital based descriptive study of 130 patients of different types of strokes. Results: Out of 130 patients 70 were male and 60 females. Majority (58%) of the patients were between 41–60 years of age. Patient presented with variable risk factors. The majority (60% male and 73% female) were hypertensive. The percentage of other factors including diabetes mellitus, atrial fibrillation, smoking, high serum cholesterol, obesity and carotid artery stenosis was observed. Conclusions: Cerebral infraction is the most common cause of stroke in our community and all the other factors that are included in our study showed their association in occurrence of cerebral infraction.Keywords:  cerebral infarction; diabetes mellitus; hypertension; smoking

Author Biographies

Saqib Malik, ATH

Department of MedicineATHAbbottabad

Alia Pervez, ATH


Zarnab Zainab, ATH



Ropper AH, Adams RD, Victor M, Brown RH, Victor M. Adams and Victor’s principles of neurology. 8th ed. New York: McGraw-Hill Medical Pub. Division, 2005; p.1382.

Hankey GJ. Potential new risk factors for ischemic stroke: what is their potential? Stroke 2006;37(8):2181–8.

Furie KL, Kasner SE, Adams RJ, Albers GW, Bush RL, Fagan SC, et al. Guidelines for the Prevention of Stroke in Patients with Stroke or Transient Ischemic Attack: A Guideline for Healthcare Professionals from the American Heart Association/American Stroke Association. Stroke 2011;42(1):227–76.

D'Agostino RB, Wolf PA, Belanger AJ, Kannel WB. Stroke risk profile: adjustment for antihypertensive medication. The Framingham Study. Stroke 1994;25(1):40–3.

Saver JL. Time is brain - quantified. Stroke 2006;37(1):263–6.

Flint AC, Duckwiler GR, Budzik RF, Liebeskind DS, Smith WS. Mechanical thrombectomy of intracranial internal carotid occlusion: pooled results of the MERCI and Multi MERCI Part I trials. Stroke 2007;38(4):1274–80.

Smith WS, Sung G, Starkman S, Saver JL, Kidwell CS, Gobin YP, et al. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke 2005;36(7):1432–8.

Lutsep HL, Rymer MM, Nesbit GM. Vertebrobasilar revascularization rates and outcomes in the MERCI and multi-MERCI trials. J Stroke Cerebrovasc Dis 2008;17(2):55–7.

Smith WS. Safety of mechanical thrombectomy and intravenous tissue plasminogen activator in acute ischemic stroke. Results of the multi Mechanical Embolus Removal in Cerebral Ischemia (MERCI) trial, part I. AJNR Am J Neuroradiol 2006;27(6):1177–82.

Smith WS, Sung G, Saver J, Budzik R, Duckwiler G, Liebeskind DS, et al. Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke 2008;39(4):1205–12.

Chen D, Roman GC, Wu GX, Wu ZS, Yao CH, Zhang M, et al. Stroke in China (Sino-MONICA-Beijing study) 1984-1986. Neuroepidemiology 1992;11(1):15–23.

Hong Y, Bots ML, Pan X, Hofman A, Grobbee DE, Chen H. Stroke incidence and mortality in rural and urban Shanghai from 1984 through 1991: findings from a community-based registry. Stroke 1994;25(6):1165–9.

Kinjo K, Kimura Y, Shinzato Y, Tomori M, Komine Y, Kawazoe N, et al. An epidemiological analysis of cardiovascular diseases in Okinawa, Japan. Hypertens Res 1992;15(2):111–9.

Hu HH, Sheng WY, Chu FL, Lan CF, Chiang BN. Incidence of stroke in Taiwan. Stroke 1992;23(9):1237–41.

Suzuki K, Kutsuzawa T, Takita K, Ito M, Sakamoto T, Hirayama A, et al. Clinico-epidemiological study of stroke in Akita, Japan. Stroke 1987;18(2):402–6.

Kay R, Woo J, Kreel L, Wong HY, Tech R, Nicholls MG. Stroke subtypes among Chinese living in Hong Kong: the Shatia Stroke Registry. Neurology 1992;42(5):985–7.

Murray CJL, Lopez AD. Global and regional cause-of-death patterns in 1990. Bull World Health Organ 1994;72(3):447–80.

Ariesen MJ, Claus SP, Rinkel GJ, Algra A. Risk factors for intracerebral hemorrhage in the general population: a systematic review. Stroke 2003;34(8):2060–5.

Rodriguez BL, D’Agostino R, Abbott RD, Kagan A, Burchfiel CM, Yano K, et al. Risk of hospitalized stroke in men enrolled in the Honolulu Heart Program and the Framingham Study: a comparison of incidence and risk factor effects. Stroke 2002;33(1):230–6.

MacMahon S, Peto R, Cutler J, Collins R, Sorlie P, Neaton J, Abbott R, et al. Blood pressure, stroke, and coronary heart disease. Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias. Lancet 1990;335(8692):765–74.

Song YM, Sung J, Lawlor DA, Davey Smith G, Shin Y, Ebrahim S. Blood pressure, haemorrhagic stroke, and ischaemic stroke: the Korean national prospective occupational cohort study. BMJ 2004;328(7435):324–5.

Tuomilehto J, Korhonen HJ, Kartovaara L, Salomaa V, Stengard JH, Pitkanen M, et al. Prevalence of diabetes mellitus and impaired glucose tolerance in the middle-aged population of three areas in Finland. Int J Epidemiol 1991;20(4):1010–7.

Wolf PA, D’Agostino RB, Kannel WB, Bonita R, Belanger AJ. Cigarette smoking as a risk factor for stroke: the Framingham Study. JAMA 1988;259(7):1025–9.

Neaton JD, Wentworth DN, Cutler J, Stamler J, Kuller L. Risk factors for death from different types of stroke. Multiple risk factor intervention trial research group. Ann Epidemiol 1993;3(5):493–9.

Lindenstrom E, Boysen G, Nyboe J. Lifestyle factors and risk of cerebrovascular disease in women: the Copenhagen City Heart Study. Stroke 1993;24(10):1468–72.

Bonita R, Beaglehole R. Smoking, drinking, and the risk of stroke. Cardiovasc Risk Factors 1993;3(4):201–6.

Fujishima M, Kiyohara Y, Ueda K, Hasuo Y, Kato I, Iwamoto H. Smoking as cardiovascular risk factor in low cholesterol population: the Hisayama Study. Clin Exp Hypertens 1992;14(1-2):99–108.

Kelley RE, Berger JR, Alter M, Kovacs AG. Cerebral ischemia and atrial fibrillation: prospective study. Neurology 1984;34(10):1285–91.

Bogousslavsky J, Van Melle G, Regli F, Kappenberger L. Pathogenesis of anterior circulation stroke in patients with nonvalvular atrial fibrillation: the Lausanne Stroke Registry. Neurology 1990;40(7):1046–50.

Bogousslavsky J, Adnet-Bonte C, Regli F, Van Melle G, Kappenberger L. Lone atrial fibrillation and stroke. Acta Neurol Scand 1990;82(2):143–6.

Mattle H, Schwerzmann M, Seiler C. Atrial fibrillation and stroke. Ther Umsch Rev Ther 2003;60(9)507–34.

Phillips SJ. Is atrial fibrillation an independent risk factor for stroke? Can J Neurol Sci 1990;17(2):163–8.

Davis PH, Dambrosia JM, Schoenberg BS, Schoenberg DG, Pritchard DA, Lilienfeld AM, et al. Risk factors for ischemic stroke: A prospective study in Rochester, Minnesota. Ann Neurol 1987;22(3):319–27.

Welin L, Svardsudd K, Wilhelmsen L, Larsson B, Tibbin G. Analysis of risk factors for stroke in a cohort of men born in 1913. N Engl J Med 1987;317(9):521–6.

Komachi Y, lida M, Ozawa H. Risk factors of stroke. Saishin Igaku 1977;32:2264–9.

Yano K, Reed DM, MacLean CJ. Serum cholesterol and hemorrhagic stroke in the Honolulu Heart Program. Stroke 1989;20(11):1460–5.

Iso H, Jacobs DR Jr, Wentworth D, Neaton JD, Cohen JD. Serum cholesterol levels and six-year mortality from stroke in 350,977 men screened for the Multiple Risk Factor Intervention Trial. N Engl J Med 1989;320(14):904–10.



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