A COMPARATIVE STUDY OF VAGINAL PROSTAGLANDIN E2 PESSARIES WITH INTRAVENOUS OXYTOCIN FOR THE INDUCTION OF LABOUR AFTER SPONTANEOUS RUPTURE OF MEMBRANES
AbstractABSTRACT:In a prospective randomized study, 60 patients were induced with 3 mg vaginal FE2 pesseriesor intravenous oxytocin.Oxytocin stimulation was associated with shorter labour and a lower incidence of abnormalcervimeteric progress, after spontaneous rupture of membranes. Out of these patients given PGE220% required a second dose after four hours of slow progress. 10% of primigravida subsequentlydeveloped abnormal labour and required augmentation by oxytocin to correct their uterinecontractions. Two caesarian sections were carried out for disproportion and remaining 58 patientswere delivered vaginally. PGE2 pesseries were not associated with an increased incidence ofhyperstimulation or sepsis. In conclusion oxytocin infusion is a safe, effective but inconvenientmethod of induction of labour, while PGE2 pesseries are safe, effective, more acceptable but anexpensive method of induction of labour.
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