• Mohammad Yousaf
  • Ahmed Badar
  • Ahmad Kamal Ansari


The effects of aging on cardiovascular and autonomic systems were evaluated through postprandial baroreceptor activity comparison between a group of young adults (n=20) and a group of elderly subjects (n=50) through measurements of pulse rate, which is an indicator of baroreceptor activity. Significant rise of pulse rate was observed in the young adults at 15, 30, 45 and 60 minutes after meal, while similar postprandial compensatory tachycardia was not found in the elderly group. The mean differences in pulse rate in young adult group at 15, 30, 45 and 60 minutes after meal were 2.05 ±0.28, 5.90 ±0.37, 5.95 ±0.37 and 3.60 ±0.42 beats /minute respectively, while the same values at the same time intervals in elderly subjects were 0.48±0.31, 1.14±0.54, 0.06 ±0.34 and -0.36±0.26 beats/minute respectively. Highly significant differences (p <0.001) were observed in the values at all postprandial time intervals between the two groups.


Robertson D, Wade D & Robertson RM. Postprandial

alteration in cardiovascular hemodynamics

in autonomic dysfunctional states. Am J Cardiol,


Guyton AC. Textbook of Medical Physiology. 7th

edition. Philadelphia. W.B> Saunders & Co., 1986,

pp 206-17 and 244-56.

Kirchheini HR. Systemic arterial baroreceptor

reflexes. Physiol Rev, 1976;56:100-76.

Smyth HS, Sleight P & Pickering GW. Reflex

regulation of arterial pressure during sleep in man.

Cir Res, 1969;24:109-21.

Sundlof G & Wallin BG. Human muscle nerve

sympathetic activity at rest. Relation to blood

pressure and age. J Physiol, 1978;274:621-37.

Brandt JL, Castleman L, Ruskin HD, Greenwald J &

Kelly Jr JJ. The effect of oral protein and glucose

feeding on splanchnic blood flow and oxygen

utilization in normal and cirrhotic subjects. J Clin

Invest, 1955;34:1017-25.

American Heart Association. Recommendations for

sphygomanometry. Am Heart J, 1969;77:147- 8.

Gribbin B, Pickering TG, Sleight P & Peto R. Effect

of age and high blood pressure on baro- reflex

sensitivity in man. Cir Res, 1971 ;424-31.

Bader H. Dependence of wall stress in the human

thoracic aorta on age and pressure. Cir Res,


Muratori G. Histological observations on the

structure of the carotid sinus in man and mammals.

In: Baroreceptors and Hypertension. Kezdi P (ed),

Oxford. Pergaman, 1967, pp 253-65.

White NJ. Heart rate changes on standing in elderly

subjects with orthostatic hypotension. Clin Sci,


Appenzeller O & Goss JE. Glucose and baroreceptor

function. Arch Neurol, 1970;23:137-46.


Most read articles by the same author(s)

1 2 3 > >>