PREVALENCE OF HEPATITIS B CARRIERS AND BLOOD GROUP FREQUENCY IN VOLUNTARY BLOOD DONORS

Authors

  • Nayla Tariq Chaudhry
  • Shahnaz Javed Khan
  • Tanvir Ali Khan
  • Munim Saeed
  • Maliha Syed
  • Javed Iqbal
  • Shahzjad Ahmed
  • Maleeha Saleem
  • Zunera Yaqub

Abstract

Infection with Hepatitis B virus is a serious hazard. A study was carried out to evaluate the prevalence rate of HBsAg carrier state among a group of 200 healthy voluntary blood donors. Blood groups and haemoglobin levels were also determined. The prevalence rate for HbsAg carrier suite was 2% (males-1.09%, females11.11%). The frequency distribution of ABO blood groups was: A- 22.7%, B- 36.35%, O- 33.85%>, and AB- 7.10%. The percentage distribution of Rh antigen was: Rh+ve- 93.44% and Rh-ve- 6.56%. Haemoglobin level, mean value ±standard deviation, for males was 13.84 ±0.95 and in case of females it was 13.02±0.53. The study reveals that females exhibit greater seropositivity, group B is the commonest and males have significantly higher Hb levels. In order to estimate HBV, blood and all blood products must be tested for HbsAg. Moreover, Hepatitis B vaccine should be included in the Expanded Programme of Immunization in our country. KEYWORDS: Hepatitis B, HbsAg, Blood groups, ABO, Rh(D), Haemoglobin

References

Deinhardt F, Abb J & Assad F. Viral hepatitis.

Bulletin of the WHO, 1983;61:203-6.

Vall Mayans M, Hall AJ, Inskip HM, et al. Risk

factors for transmission of hepatitis B virus to

Gambian children. Lancet 1990;336:1107-9.

Thursz MR, Kwiatkowski D & Alisopp CEM, et al.

Association between an MHC Class II allele and

clearance of hepatitis B virus in the Gambia. N Engl

J Med, 1995;332:1065-9.

Blumberg BS & Alter HJ. Precipitating antibodies

against a serum protein (Australia antigen in the

blood of a transfused haemophilia patient). J Clin

Inv, 1965;44:1029.

Zeldis JB, Shabib SM & Tufenkejl H. Diagnosis of

viral hepatitis (Editorial). Annals of Saudi Medicine,

; 15(1): 1-5.

Malik 1A, Tariq WVZ, Hassan ZU & Mahmood A.

Sub-classification of hepatitis B vims carriers.

JCPSP, 1996;6(1):4-5.

Attique MUH, Yousaf M, Haleem A & Hassan A.

Prevalence of hepatitis B virus in liver diseases in

Bahawalpur. JPGMI, 1990;4(1): 139-42.

Yousaf M & Yousaf N. Prevalence of hepatitis B

carriers among health care workers. Pak J Med Res,

;27:168-9.

Jabeen M, Hussain R, Siddiqui SA, Fayyaz A &

Saleem M.Prevalence of hepatitis B surface antigen

(HbsAg) in doctors, medical students and

paramedical staff working in Sir Ganga Ram

Hospital. Lahore. Pak J Med Res, 1995:34:172- 5

Alter MJ. Hadler SC & Margolis HS, et al. the

changing epidemiology of hepatitis B in United

States. JAMA, 1990;263:1218-22.

Parveen N. ABO and subgroup A in the Lahore

population. JPMA, 1987;37:200-1.

Jamal A. Ahmed MS. Ahmad A, Zafar MN & Syed

S. ABO and A subgroups in Karachi population.

JPMA, 1988;38:199-200.

Mustansar M & Ah I. Iron deficiency in women and

children specialists. Pak J Med Sci, 1995;

(4):323-5.

Hussain S, Khan AB, Ansari JK, Fazal I & Orakzai

A. Incidence and clinical aspects of hepatitis B in

naval hospital Karachi. PAFMJ, 1994;44(2):28-33.

Burney Ml. Spectrum of liver disease as studied at

the National Health Laboratories. National Seminar

on Liver Disease (Proceedings). PMRC Monograph

No 2, 1977;44.

Janjua IM & Hussain M. Hepatitis B vims surface

antigenaemia in voluntary blood donors and patients

with acute hepatitis. Pak J Med Res, 1990;29:160-2.

Malik 1A & Tariq WIJZ. Viral hepatitis in Pakistan

(Editorial). Pak J Path, 1993;4:1-5.

Lin HJ, Lai CL & Lau JYN. et al. Evidence for

intrafamilial transmission of hepatitis B virus from

sequence analysis of mutant HBV DNAs in two

Chinese families. Lancet, 1990;336:208-12.

Qureshi H. Post exposure prophylaxis of hepatitis B.

JPMA, March 1988;62-4

Nutritional anaemias. WHO Technical Report

Series, I972;502:29.

Dacies JV & Lewis SM. Practical Haematology.

Reference ranges and normal values. London, 7th

edition. Churchill Livingstone, 1991; 12.

Williams JR % Flowerdew ADS. Uptake of

immunization against hepatitis B among surgeons in

Wessex Regional Health Authority. BMJ,

:301:154.

Integrating hepatitis B vaccine into EPI programs

(WHO Special Report). Pak Paed J, 19; 17:85-7.

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