ABO BLOOD GROUPS AND SERUM LIPIDS IN PATIENTS WITH ISCHAEMIC HEART DISEASE

Authors

  • Israr Ahmed Akhund
  • Anwar Ali Akhund
  • Irshad Ali Alvi
  • Hafeez ullah
  • Ahmed Kamal Ansari

Abstract

To assess the association of Blood Groups with Serum Lipids in patients with ischaemic heart disease, twohundred patients were reviewed. Patients belonging to blood group A had higher mean serum cholesterol levels(p<0.01) than those belonging to Groups O, B and AB. Slightly higher than upper normal values of serum cholesterolwere also seen in group A healthy control. Statistical analysis revealed that the blood group A was an independentrisk factor for the development of Ischaemic heart disease.

References

Allan T.M, and Dawson A.A: ABO blood groups and

ischaemic heart disease in men. Br. Heart. J. 1977; 30:

-82.

Morris T: ABO blood groups in occlusive and ectatic

arterial disease. Br. J. Surg, 1973; 60; (11): 892-93.

Morton N.E: Genetic markers in atherosclerosis. A

review; J. Med. Genet, 1976; 13:81-90.

Whincup D.G.C, Phillips A.N, Shaper A.G: ABO blood

groups and ischaemic heart disease in British men.

B.M.J. 1990; 1679-82.

Gillum R.F, Hyattsville, Maryland: Blood groups,

serum cholesterol, serum uric acid, blood pressure and

obesity in adolescents.

Tarjan Z, Tonelli M, Duba J, Zorandi A:

Correlation between ABO and RH blood groups, serum

cholesterol and ischaemic heart disease in patients

under going coronarography. Orv. Hetil, 1995;

(15):767-769.

Oliver M.F, Geizerova H, Gumming R.A. Heady J.A:

Serum cholesterol and ABO and Rhesus blood groups

Lancet, 1969; ii: 605-606.

Hagerup P.H, and Skov F: Serum cholesterol, serum

triglycerides and ABO blood groups in population of 50

years old Danish men and women. Am. J. Epid, 1972;

(ii): 99-103.

Comenwett J.L, Davis J.T.J.R, Garrett E: ABO blood

groups and serum lipids in female atherosclerosis. J.

Cardiovac. Surg. 1983; 24: 658-661.

Dacie J.V, and Lewis S.M (1984): in practical

haematology. Churchill Livingstone, Edinburgh.

Varley H, Govenlock A.M, Bell M: Practical clinical

Biochemistry. Vol: 1 London: William Heinemann

Medical books, 1980; 388-95.

Richmond W: Estimation of Cholesterol by enzymatic

method. Clin. Chemist., 1973; 19:1350-2.

Levy RA: Enzymatic determination of LDLcholesterol. Clinical chemistry, 1981; 27:653-62.

Garrison R.J, Havlik R.J. Harris R.B. Feinleib M.

Kannel W.B, Padgett S.J: ABO blood groups and

cardiovascular disease. Atherosclerosis, 1979; 25:311-

Medalie J.H. Papier B.A. Goldbout U, Levene C,

Dreyfuss F, Oron D: Blood groups and hypertension.

Isr. J. Med. Sci, 1973; 9:989-94.

Fox M.H, Webber L.S, Srinivasan S.R, Thurmon T.F,

Berenson G.S: ABO blood group associations with

cardiovascular risk factor variables, I: serum lipid and

lipoproteins: Hum. Biol, 1981; 53: 411-437.

Boreckis L.B. Elston R.C, Rosenbaum P.A, Srinivasan

S.R, Berenson G.S: ABO associations with blood

pressure, serum lipid and lipoproteins, and

anthropometric measures. Hum, Hered, 1985; 35:161-

Garrison R.J, Havlik R.J, Harris R.B: ABO blood

groups and cardiovascular disease. Atherosclerosis,

; 25:311- 318.

Langman M.J.S, Foote J, Elwood P.Q, Pyrie Dr: ABO

and Lewis blood groups and serum cholesterol: Lancet,

; ii: 607-609.

Horby J, Gyrtrub H.J, Grande P, Vestergaard, A:

Relation of serum lipoproteins and lipids to the ABO

blood groups in patients with intermittent claudication.

J. Cardiovac. Surg, 1989;30:533-37.

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