EFFECT OF ORAL AND INJECTABLE CONTRACEPTIVES ON SERUM CALCIUM, MAGNESIUM AND PHOSPHORUS IN WOMEN

Authors

  • ABDUL HAMEED
  • TASNEEM MAJEED
  • SHAHID RAUF
  • MOHAMMAD ASHRAF
  • M. ASIF JALIL
  • NASR ULLAH
  • ALTAF HUSSAN
  • ROOZEENA NOREEN

Abstract

Background: This study aims at evaluating serum calcium, magnesium and phosphorus levels in women taking oral and injectable contraceptives.Methods: Serum calcium, magnesium and phosphorus were measured in 50 women taking oral contra ptives (Lofeminal) and 50 women takinginjectable contraceptive (Depo-medroxy progesterone acetate and Norigest). These women were used as controls before starting thesecontraceptives. Results: There was significant decrease in serum levels of calcium, magnesium and phosphorus in women taking oral contraceptivesbut there was significant increase in these minerals in women taking injectable contraceptives. Conclusions: It is suggested that these contraceptivesshould be used with due care and with proper investigations of the women before and during the therapy.

References

Dale E, Simpson GR. Serum magnesium levels of women on

oral or long acting inject able presentational contraceptives.

Obstet Gaec. 1972;39-115.

Farese RV. Calcium as a mediator of adrenocorticotrophic

hormone on adrenal protein synthesis. Science. 1971:173-

Nasim JR, Servile PD and Malign L. The effect of stibloestrol

on urinary phosphate excretion. Clinical Science. 1955; 15-

Paschhin K.E, Rahoff AE, Cantarow AE and Rupp JJ. Effect

of non-estrogenic (Depo-Medroxy progesterone acetate) on

calcium metabolism. Clin Endocrinology (Ed.3), 1967.

Pulhhinen MO and Willman K. Oral contraceptives and

phosphorus metabolism Br Med J; l967;2-574.

Reifenstein EC and All Right F. Metabolic effects of steroid

hormones in osteoporosis. J Clin Invest. 1947; 24-26.

Simpson GR and Dale E. Serum level of phosphorus,

magnesium and calcium in women utilizing combination of

oral or long acting injectable progestational contraceptive. J

Fertility and Sterility. 1972;23;323-330.

Thuer C.R. Effect of oral contraceptive agents on vitamin and

mineral needs. A review J Reprod. 1972; 8:13-19.

Thin CG. The effect of an oral contraceptive agent on the

concentration of calcium and magnesium in plasma

erythrocytes and platelets in women.

Young MM, Jasnic C, Smith DA and Nordin BEC. Some

effects of ethanol estradiol on calcium and phosphorus

metabolism in osteoporosis. .1 Clin Science. 1968;34-411

Seegercs WH. Blood clotting enzymology New York

academic press. 1967.

Waxher WEC and Parise AA. Magnesium metabolism N

Engl1 Med. 1968:278

Issue

Vol. 13 No. 3 (2001): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

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