EFFECT OF ORAL AND INJECTABLE CONTRACEPTIVES ON SERUM CALCIUM, MAGNESIUM AND PHOSPHORUS IN WOMEN
AbstractBackground: This study aims at evaluating serum calcium, magnesium and phosphorus levels in women taking oral and injectable contraceptives.Methods: Serum calcium, magnesium and phosphorus were measured in 50 women taking oral contra ptives (Lofeminal) and 50 women takinginjectable contraceptive (Depo-medroxy progesterone acetate and Norigest). These women were used as controls before starting thesecontraceptives. Results: There was significant decrease in serum levels of calcium, magnesium and phosphorus in women taking oral contraceptivesbut there was significant increase in these minerals in women taking injectable contraceptives. Conclusions: It is suggested that these contraceptivesshould be used with due care and with proper investigations of the women before and during the therapy.
Dale E, Simpson GR. Serum magnesium levels of women on
oral or long acting inject able presentational contraceptives.
Obstet Gaec. 1972;39-115.
Farese RV. Calcium as a mediator of adrenocorticotrophic
hormone on adrenal protein synthesis. Science. 1971:173-
Nasim JR, Servile PD and Malign L. The effect of stibloestrol
on urinary phosphate excretion. Clinical Science. 1955; 15-
Paschhin K.E, Rahoff AE, Cantarow AE and Rupp JJ. Effect
of non-estrogenic (Depo-Medroxy progesterone acetate) on
calcium metabolism. Clin Endocrinology (Ed.3), 1967.
Pulhhinen MO and Willman K. Oral contraceptives and
phosphorus metabolism Br Med J; l967;2-574.
Reifenstein EC and All Right F. Metabolic effects of steroid
hormones in osteoporosis. J Clin Invest. 1947; 24-26.
Simpson GR and Dale E. Serum level of phosphorus,
magnesium and calcium in women utilizing combination of
oral or long acting injectable progestational contraceptive. J
Fertility and Sterility. 1972;23;323-330.
Thuer C.R. Effect of oral contraceptive agents on vitamin and
mineral needs. A review J Reprod. 1972; 8:13-19.
Thin CG. The effect of an oral contraceptive agent on the
concentration of calcium and magnesium in plasma
erythrocytes and platelets in women.
Young MM, Jasnic C, Smith DA and Nordin BEC. Some
effects of ethanol estradiol on calcium and phosphorus
metabolism in osteoporosis. .1 Clin Science. 1968;34-411
Seegercs WH. Blood clotting enzymology New York
academic press. 1967.
Waxher WEC and Parise AA. Magnesium metabolism N
Engl1 Med. 1968:278
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.