INSULIN THERAPY IN NWFP PAKISTAN
AbstractThe management of Type I and Type II DiabetesMellitus has improved because of tremendousimprovement in Insulins over the years, butunfortunately majority of patients in our countrycannot afford these, especially the human insulin, andare deprived of the benefits. Access to insulin shouldbe regular and uninterrupted.Insulin therapy has changed the outlook of Type I -IDDM from certain death to almost normal existence.The discovery of Banting and Best in 1921, was thegreatest breakthrough in this field. Since thencontinuous improvement in Insulins is taking place. InI980\s Recombinant DNA origin insulin came intouse. These insulins are less antigenic, purer, betterabsorbed and lesser doses are required as compared toanimal origin insulins. Human Insulin was firstproduct of biotechnology to enter the clinical Arena2.By 1950 exact structure of insulin molecule wasknown3. In developed countries the prognosis ofDiabetes has dramatically improved over last twentyyears with life expectancy approaching towardsnormal, especially in Denmark4.
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