• Tariq Mufti
  • M. Saeed Khan
  • Muzher -U- Dua
  • Farah Waqar


An old lady of 58 years’ age presented with a huge softtissue mass over left pectoral region which wasgradually increasing in size over the last 5-ycars.Patient also gives history' of recent appearance ofconstant dull pain and low grade fever (<100Fo) for thelast 3-4 months. CT Scan revealed a soil tissue subcutaneous mass extending from the dermis downwardswithout rib erosion. X-Ray chest clear and USGabdomen was normal. Excisional biopsy revealedDermatofibrosarcoma protuberans. After woundhealing, external radiation on 10Mev electron beam(Varianclinac-20) with direct anterior fieldencompassing nearly upper 2/3 of left chest wall anddelivering a tumor dose of 48 grays at I cm depth in 16treatments. 3 ’A weeks’ time as ϵ 300 cgys daily.The tumor bed can be radiated on cobolt -60 (Megavoltage beam) with tangential fields to mid line doseof 60 grays in 30 fractions for 6 weeks


Hippocrates The theory and practice of medicine.

Runes DD. Kleman T(eds) Secaucus NJ, Citadel

press 1964

Gloster HM JR..DFSP. J Am. Acad. Dermatol

; 35:355

Gutierrez G. DFSP. Inj. J. Dermatol. 1984; 23:396

Alguacil Garcia A and Go liner JR. Histogenesis of

DFSP an ultra-structural study. Am J Clin. Pathol.


Eilber FR, Morton Dl and Econoomon JS. The soft

tissue sarcomas, Orlando FL & New York. 1987.

Fletcher CD, Evans BJ, Mekee PH. DFSP. A

clinic-pathological and immuno-histochemical!

study, a review of literature. Histopathology

:9: 921.

Taylor HB. Helwig EB. DFSP A study of II5 cases.

Cancer. 1962.15; 717.

Garg SK, Subbuswamy SG, Lawrie JH. DFSP in

northern Nigeria. A clinicopathoiogical review of

cases. Clin Oncol 1978;4: 113.

. Burkhardt BR, Soule EH, Wink Elman RK et al.

DFSP. A study of 56 cases. Am J. Surg. 1966. 11;

Mcpeak CJ, Druz T, Nicestri AD. DFSP. An

analysis of 86 cases, 5 with metastasis. Ann. Surg.

166; 803.

Rink PA, Habermalz HJ, Loccek H: Effective

radiotherapy in one case of DFSP Starling

Therapies. 1982 158:681.

Hajdu SI: Pathology of soft tissue sarcoma.

Philadelphia Lea and Febiger. 1979.

Kobayashi T el al: a case of Bednar tumor.

dermatology. 1997.195:87.

Eigen GW et al: Bednar tumor occurring in site of

prior immunization. J. Am. Acadmi. Dermatol


Hashimoto K, Brownstein Mh Jsceobi FA: DFSP.

Arch. Dermatol 1974 110:874.

Qzzello L & Hamel SJ: the histolytic nature of

DFSP. Tissue culture and electron microscopic

study Am J Clin Pathol 1976 65:136

Cantin J, Meneer JP. Chu PC el al the problem of

local recurrence after surgical excision ann. Surg


Schieber W. Grham P: an experience with sarcoma

tissue in adults Surgery 1962 52 295

Albright SIT treatment of skin cancer using

multiple modalities J Am Acad Dermatol 1982 7

Hruza GJ Mohs micro graph surgery, oto larygol

Clin. North Am 1990 23 845

Mohs FE & Blanchard L Microscopically

controlled for extra memory pajet's disease arch

Dermatol 1979 115. 706

Rowe DE. Carroll RJ, Dayel long term the

recurrence rate in previously untreated skin cancer

J. Dermatol Surg Oncol 1989 15:315

Radnar D et al. Mohs micrographic surgery for the

treatment of DFSP J. Am. Acad Dermatol 1997 37

Robinson J: DFSP resected by mohs surgery. J Am.

Acad Dermatol 1985. 12:1093

Suit HD. Mankein HJ, wood WO. Props KM. Preoperative, intra operative & post-operative

radiation in the treatment of soft tissue sarcoma.

Cancer. 1985 55: 2659-26667.

Tepper JE, Suit HD. The role of radiotherapy in

soft tissue sarcoma. Cancer invest 1985 3: 587-

Kiel KD, Suit HD Radiation therapy in the

treatment of aggressive fibromatosis (desmoid

tumors). Cancer 1985 54. 2041-2055.

Kinsella TJ, Glastein E. Clinical experience with

i/v radio sanitizers in unresectable sarcoma. Cancer

59 908-915.

Tepper JE, suit HB. radiation therapy alone for

soft tissue sarcoma. Cancer 1985 56: 475.

Atkin L, Garvan Jm. Neuton NT. behaviour and

management of soft tissue sarcoma. Cancer 1963

: 1552

Martin RG. Lindberg RD, Russel WO. Preoperative radiotherapy & surgery in the

management of soft tissue and bone sarcoma. PB

-307 Chicago year book medical publishers

Rosenberg SA. suit HD baker LH et al. Soft tissue

and bone sarcoma in Devita. cancer principle and

practice of oncology. Philadelphia Lippin cortt

pp 1036-1068.

Suit HD proppe KH: Multi-disciplinary decisions

in oncology. Soft tissue sarcoma. New York

Pergoman press 1982.

Suit HD. Proppe KH, Mankin HJ et al: Preoperative radiotherapy for soft tissue sarcoma.

Cancer 1981 47: 2267- 2774.

Meneer GP, cantin J, Chu F et al: Effective of

radiotherapy for soft tissue sarcoma. Cancer 1968.

;391 -397

Mittal D, Emami B. Sapareto S et al., Effects of

combined hyperthermia and radiation on the RIF-1

murine tumor. Cancer 1984 54:2889.

Raney B, Jr.: Soft tissue sarcoma in

adolescent in tibbi CK (ed). Major topics in

adolescent oncology) Mamt Kisco, Future

publishing 1987 PP 221 -240

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