AbstractParathyroid carcinoma is a very rare cause of primary hyperparathyroidism and these tumors areusually hyper-functioning as compared to other malignant endocrine tumors. Surgery is the onlyeffective primary treatment. We report a patient, who presented with pathological fracture offemur, hypercalcemia, bilateral renal stones, markedly raised Parathormone levels and palpablemass in the neck. Parathyroid adenoma was initially diagnosed and localized at left lower gland bySestamibi scan and ultrasonography. She underwent surgery and enlarged parathyroid gland wasremoved. Intra operatively there was no evidence of local invasion or lymph nodes involvementbut biopsy report suggested malignancy.Keywords: Parathyroid carcinoma, Adenoma, Primary hyperthyroidism, Sestamibi scan.
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