CIRCULATING IMMUNE COMPLEX DURING RAMADAN
AbstractBackground: Fasting during Ramadan represent one of the five pillars of the Islamic religion. Soit is important to know the effect of this kind of fasting on people's life especially on their health.The purpose of this study was to show the effect of fasting during Ramadan on circulatingimmune complex (CIC) level and immune system. Methods: The CIC levels were measuredbefore and after Ramadan by polyethylenglycole method. The blood samples were examinedusing quantitation chemiluminesence and circulating immune techniques. The results wereanalyzed using t-test and calculated coefficient correlation between CIC before and afterRamadan. Results: There was no significant difference between the CIC level before and afterRamadan. Conclusion: According to the results, fasting during Ramadan does not have bad effecton immune system of healthy people.Keywords: CIC; Ramadan; Fasting; Immune complex
Kadri N, Tilane A, El Batal M, Taltit Y, Tahiri SM,
Moussaoui D . Irritability during the month of Ramadan.
Psychosom Med 2000; 62: 280-285.
Reeves J. Pregnancy and fasting during Ramadan. BMJ1992;
Rashed AH: The fast of Ramadan. BMJ 1992; 304:521-522.
Abdalla AH, Shaheen FA, Rassoul Z, Owda AK, Popovich
WF, Mousa DH, et al. Effect of Ramadan fasting on Moslem
kidney transplant recipients. Am J Nephrol 1998; 18:101-
Steele RW. Clinical applications of chemiluminescence of
granulocytes. Rev Infect Dis 1991; 13: 918-925
Easmon CS, Cole PJ, Williams AJ, Hastings M. The
measurement of opsonic and phagocytic function by
Luminol-dependent chemiluminescence. Immunology 1980;
Ballart IJ, Estevez ME, Diez RA, Sen L . Comparison of
candida killing activity measured by chemiluminescence and
cytomorphological methods in human phagocytes. J Immunol
Methods 1987; 97:263-268.
Ingham KC. Precipitation of proteins with polyethylene
glycol. Methods Enzymol 1990; 182:301-306.
Chia D, Barnett EV, Yamagata J, Knutson D , Restivo C,
Furst D. Quantitation and characterization of soluble immune
complexes precipitated from sera by polyethylene glycol
(PEG). Clin Exp Immunol 1979; 37:399-407.
Virella G, Hipp WA, John JF Jr, Kahaleh B, Ford M,
Fudenberg HH. Nephelometric detection of soluble immune
complexes: methodology and clinical applications. Int Arch
Allergy Appl Immunol 1974; 58:402-410.
J Ayub Med Coll Abbottabad 2007; 19(2)
Hoffken K, Bestek U, Sperber U, Schmidt CG. Quantitation
of immune complexes by nephelometry. J Immunol Methods
Cooper KM, Moor M. Critical aspect of immune complex
assay employing polyethylene glycol. J Immunol Methods
Soltis RD, Hasz DE. The effect of serum 11 immunoglobulin
concentration on immune complex detection by polyethylene
glycol. J Immunol Methods 1983; 57: 275-282.
Lambert PH, Dixon FJ, Zubler RH, Agnello V, Cambiaso C,
Casali P, et al. A WHO collaborative study for the evaluation
of eighteen methods for detecting immune complexes in
serum. J Clin Lab Immunol 1978;1:1-15.
McDougal JS, Hubbard M, Strobel PL, McDuffie FC.
Comparison of five assays for immune complexes in the
rheumatic diseases: performance characteristics of the assays.
J Lab Clin Med 1982;100:705-719.