FREQUENCY OF PRIMARY SOLID MALIGNANT NEOPLASMS IN DIFFERENT AGE GROUPS AS SEEN IN OUR PRACTICE
AbstractBackground: To determine in a large series of surgical biopsies, the frequency of varioushistologic types of primary solid malignant neoplasms in males and females in different agegroups. Methods : A retrospective study of 20,000 consecutive surgical biopsies reposted in thesection of histopathology, AKU in 2004. Results: Malignant neoplasms are commonest in thefifth and sixth decades of life. The commonest malignant neoplasms in the first decade wereHodgkin’s lymphoma and Wilm’s tumor in males and females respectively. In the second decade,osteosarcoma in males and Ewing’s sarcoma / PNET in females. In the third decade, colorectaladenocarcinoma in males and infiltrating Ductal carcinoma of breast in females. In the fourthdecade, squamous cell carcinoma of oral cavity in males and infiltrating ductal carcinoma ofbreast in females. In the fifth decade squamous cell carcinoma of oral cavity in males andinfiltrating ductal carcinoma of breast in females. In sixth decade, squamous cell carcinoma of oralcavity in males and infiltrating ductal carcinoma of breast in females and in the seventh decade,prostatic adenocarcinoma in males and infiltrating ductal carcinoma of the breast in females.Above age of 70 years, the commonest malignant were again prostatic adenocarcinoma in malesand infiltrating ductal carcinoma of breast in females. Conclusion: Malignant neoplasms arecommonest in the fourth, fifth and sixth decades of life.
Jamal S, Moghal S, Mamoon N, Mushtaq S, Luqman M,
Anwar M. The pattern of malignant tumor registry data
analysis, AFIP, Rawalpindi, Pakistan (1992-2001). J Pak Med
Assoc. 2006; 56(8): 359-62
Cancer registry and clinical data management (CRCDM),
Shaukat Khanum Memorial Cancer Hospital and Research
Centre (SKMCH and RC). Report based on cancer cases
registered at SKMCH and RC from Dec 1994- Dec 2006 and
in 2006. Released June, 2007.
Straus DJ, Filippa DA, Lieberman PH, Koziner B, Thaler HT,
Clarkson BD. The Non- Hodgkin’s lymphomas. I. A
retrospective clinical and pathological analysis of 499 cases
diagnosed between 1958 and 1969. Cancer. 1983;51(1):101-9.
Kozakewich H, Perez-Atayde AR, Goorin AM, Wilkinson
RH, Gebhardt MC, Vawter GF. Osteosarcoma in young
children. Cancer. 1991 ; 67(3) : 638-42.
Kissane JM, Askin FB, Nesbit ME Jr, Vietti T, Burgert EO Jr,
Cangir A et al. Sarcoma of bone in childhood: pathologic
aspects. Natl Cancer Inst Monogr. 1981; (56) : 29-41
Jamal S, Mamoon N, Mushtaq S, Luqman M. Pattern of
childhood malignancies: study of 922 cases at Armed Forces
Institute of Pathology (AFIP), Rawalpindi, Paksitan. Asian
Pac J cancer Prev. 2006; 7(3):420-2.
Shah SH, Pervez S, Hasan SH. Frequency of malignant solid
tumors in children. J Pak Med Assoc. 2000; 50(3): 86-88.
Maitra A, Kumar V. Diseases of infancy and childhood.
Tumors and tumor like lesions of infancy and childhood. In:
Pathologic Basis of Disease, Kumar V, Abbas AK, Fausto N
eds. 7th edition 2004, Elsevier Inc: 469-508.
Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world
cancer burden. Globocan 2000. Int J cancer 2001; 94(2) :153-6
Boyle P, Zaridze DG, Smans M. Descriptive epidemiology of
colorectal cancer. Int J Cancer. 1985; 36(1): 9-18
Schlumberger MJ. Papillary and follicular thyroid carcinoma.
N Engl J Med. 1998; 338(5) :297-306
Yang PC, Davis S. Incidence of cancer of the esophagus in the
US by histologic type. Cancer 1988 ; 61(3) : 612-7
Cannistra SA, Niloff JM. Cancer of the uterine cervix. N Engl
J Med. 1996; 334(16): 1030-8.
Nelson WG, De Marzo AM, Isaacs WB. Prostate cancer. N
Engl J Med. 2003; 349(4) : 366-81.
Voigt LF, Weiss NS. E pidemiology of endometrial cancer.
Cancer Treat Res. 1989; 49: 1-21
Bhurgri Y, Bhurgri A, Hassan SH, Zaidi SH, Rahim A,
Sankaranarayanan R et al. Cancer incidence in Karachi,
Pakistan: first results from Karachi Cancer Registry. Int J
Cancer. 2000; 85(3): 325-9.
Bhurgri Y, Bhurgri A, Hasan SH, Usman A, Faridi N, Malik J
et al. Cancer patterns in Karachi division (1998 – 1999). J Pak
Med Assoc. 2002; 52(6):244-6.
Bhurgri Y, Pervez S, Kayani N, Bhurgri A, Usman A, Bashir I
et al. Cancer profile of Larkana, Pakistan (2000 – 2002). Asian
Pac J Cancer Prev. 2006; 7(4):518-21.
Bhurgri Y, Bhurgri A, Pervez S, Bhurgri M, Kayani N,
Ahmed R et al. Cancer profile of Hyderabad, Pakistan 1998 –
Asian Pac J Cancer Prev. 2005; 6(4): 474-80.
Jemal A, Murray T, Samuels A, Ghafoor A, Ward E, Thun
MJ. Cancer statistics, 2003. CA Cancer J Clin. 2003 Jan –
Feb; 53 (1): 5-26.
Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward
E et al.: American Cancer Society. Cancer Statistics, 2004. CA
Cancer J Clin. 2004; 54(1):8-29.
Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor
A et al. Cancer statistics, 2005. CA Cancer J Clin. 2005 Jan –
Feb; 55(1): 10-30.
Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, Thun
MJ. Cancer statistics, 2006. CA Cancer J Clin. 2006;
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.