• Zubair Ahmed
  • Najamul Sahar Azad
  • Fouzia Rauf
  • Nausheen Yaqoob
  • Akthar Husain
  • Aamir Ahsan
  • Rashida Ahmed
  • Naila Kayani
  • Shahid Pervez
  • Sheema H Hassan


Background: To determine in a large series of surgical biopsies, the frequency of varioushistologic types of primary solid malignant neoplasms in males and females in different agegroups. Methods : A retrospective study of 20,000 consecutive surgical biopsies reposted in thesection of histopathology, AKU in 2004. Results: Malignant neoplasms are commonest in thefifth and sixth decades of life. The commonest malignant neoplasms in the first decade wereHodgkin’s lymphoma and Wilm’s tumor in males and females respectively. In the second decade,osteosarcoma in males and Ewing’s sarcoma / PNET in females. In the third decade, colorectaladenocarcinoma in males and infiltrating Ductal carcinoma of breast in females. In the fourthdecade, squamous cell carcinoma of oral cavity in males and infiltrating ductal carcinoma ofbreast in females. In the fifth decade squamous cell carcinoma of oral cavity in males andinfiltrating ductal carcinoma of breast in females. In sixth decade, squamous cell carcinoma of oralcavity in males and infiltrating ductal carcinoma of breast in females and in the seventh decade,prostatic adenocarcinoma in males and infiltrating ductal carcinoma of the breast in females.Above age of 70 years, the commonest malignant were again prostatic adenocarcinoma in malesand infiltrating ductal carcinoma of breast in females. Conclusion: Malignant neoplasms arecommonest in the fourth, fifth and sixth decades of life.


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