PREVALENCE OF HEPATITIS B SURFACE ANTIGEN CARRIER STATE IN PATIENTS WITH LICHEN PLANUS–REPORT OF 200 CASES FROM LAHORE, PAKISTAN
AbstractBackground: To determine the prevalence of hepatitis B surface antigen carrier state in patientswith lichen planus. Methods: A quasi experimental cross sectional study was done at Departmentof Dermatology, Shaikh Zayed Federal Postgraduate Medical Institute, Lahore, Pakistan, fromApril 2003 to March 2005. Two hundred clinically diagnosed cases of LP and equal number ofpatients with other dermatoses not reportedly associated with hepatitis B virus (HBV) infection(control group) were collected from Skin Out Patient Department. They were screened forhepatitis B surface antigen (HBsAg) by Enzyme Linked Immunosorbent Assay (ELISA).Statistical analysis was done by using SPSS package version 11. Results: Out of 200 patients ofeach group, three patients with LP and seven patients from control group were positive forHBsAg. The test of significance for proportions revealed that there was no significant difference(p>0.1) between two groups. Conclusion: No association between HBsAg carrier state and LPwas found in our study.Key Words: Lichen Planus; Hepatitis B surface antigen.
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