ITRACONOZOLE THERAPY IN TINEA V ERSICOLOR

Authors

  • Imranullah Khan
  • Ahsan Hameed
  • Shad Muhammad Wazir
  • Mian Mujahid Shah

Abstract

The efficacy of itraconazole was assessed in an open trial in 60 patients with wide spread disseminated lesions ofTinea versicolor confirmed by direct microscopy. The patients were allocated randomly to one of the two treatmentregimens. 200 mg once daily for 7 days or 100 mg once daily for 15 days. On assessment 3 weeks after the end of thetreatment. 50 patients were healed. 4 had mild residual lesions. 4 had considerable residua! lesions, and 2 hadrelapsed. Two patients reported pain in the abdomen. Two patients reported nausea, vomiting and dyspepsia. Twopatients had mild elevation of SOOT, and SOFT. Conclusion: Treatment of tinea versicolor with itraconozole 200mgday for 7 days or l00 mg day for 15 days is recommended.

References

Robert s, S.O.B, pitrysporum orbiculare incidence and

distribution on clinically normal skin. Br. J. of

Dermatology (1969a) 81:264.

Faergman, J. and Fredikson, T. Tinea versicolor with

regard to seborrheic dermatitis. Archives of

Dermatology, 1979;115: 966.

Burke, R.C. Tinea versicolor: Susceptibility factors and

experimental infections in human beings. Journal of

investigative dermatology (1961); 36: 389.

Savin, R.C, Systemic itraconozole in tinea vesicular: a

double blind examination and 1 year follow up. Journal

of American Academy of Dermatology 1984; 10: 824.

Janssen Pharmaceutica (1984) RS 1211 Basic Medical

Information Brochure, August 1984

Del Palacio Hernanz A. Delgado Vicente S. Menendez

Romes. Randomized comparative clinical trial of

itraconozole and selenium sulphide shampoo for the

treatment of tinea versicolor Rev Infect. Dis. 1987.

(Suppl-l)

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