EFFECT OF LISINOPRIL ON MICROALBUMINURIA
AbstractThe purpose of this study was to evaluate the effect of Lisinopril on microalbuminuria in non- insulin dependentdiabetic hypertensive patients. One hundred and twenty patients were divided into two groups. Croup-A was givenplacebo of Lisinopril and Group-B was given Lisinopril in a fixed dose of 10 mg once daily for two weeks. Comparisonof microalbuminuria before and after the treatment showed a decrease in microalbuminuria level in patients treatedwith Lisinopril.
I Philip R. How to treat hypertension in diabetic
patients? Postgraduate Med Hypertens Diabetes 1987;
Viberti GC. 1 Hill RD. Jarret RJ and Keen 11.
Microalbuminuria as a predictor of clinical
nephropathy in insulin dependent diabetes mellitus.
Lancet 1982; 1 1430.
Crepaldi G. Carraro A. Broccoe et al. Hypertension and
noninsulin dependent diabetes. A comparison between
an angiotension converting enzyme inhibitor and a
calcium antagonist. Acta Diabetol 1995; 32(3): 203-8.
Brenner BM. Meyer TW and Hostetler TH. Dietary
protein intake and the progressive nature of kidney
disease. N. F.ng .1 Med 1982. 307: 652.
Hostetter Th. Rennke HG and Brenner BMV The case
for internal hypertension in the initiation and
progression diabetic and other glomerulopathies. Am .1
Med 1982:72 375.
Remuzzi A. Benigni A. Malanchini B et al. ACL
inhibition prevents renal failure and death in
uninephrectomized MWF/Ztn rats. Kidney Int. 1995;
Barkis GL, Copley JB. Vicknair N et al. Calcium
channel blockers versus other antihypertensive therapy
on progression of NIDDM associated nephropathy.
Kidney Int. 1996: 50(5): 1641-50.
Agardh CP. Garcia P.l. Charbannel B et al. Greater
reduction of urinary albumin excretion in hypertensive
type-11 diabetic patients with incipient nephropathy by
Lisinopril than by nifedipine .1 Human Hypertens
; 10(3): 185-92.