• M. Zamir Ahmad Akbari
  • Muhammad Sarwar Bhatti
  • Muhammad Shakoor


Background: Smoking is one of the major risk factors in the genesis of coronary atherosclerosis and development ofcoronary heart disease. Smoking which is recognized as a major risk factor for the development of ischaemic heartdisease may lead to alter the normal plasma lipoprotein pattern. Methods: Fifty adult smokers were selected alongwith thirty normal controls. Lipid profile was studied and estimations of cholesterol, total lipids, triglycerides. HDL.LDL. VLDL and chylomicrons were made. Results: All these parameters except HDL level were significantlyincreased in smokers while HDL level was significantly decreased, showing greater risk of these persons toatherosclerosis and coronary heart disease (CHD). Various ratios like LDL/HDL. VLDL/HDL. TG/HDL and TC/HDLwere calculated to find out the risk of atherosclerosis and CHD so that early measures could be adopted to avoidcomplicated disease process.


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