• M. Hussain Khan
  • Syed Humayun Shah


Background: A small number of persons with Rh-negative blood have red blood cells that are not directly agglutinatedby anti D during routine testing for 'Rh' antigen, but that do react when the D-typing test is converted to the indirectantiglobulin test, which is Du' test. Cells thus identified are then designated as 'Du' cells. This study was done to assessthe incidence of ‘Du’ patients in Rh negative obstetrics patients. Methods: A total of 1500 pregnant women werescreened for Rh antigen. The red blood cells of the D negative subjects were then tested by indirect method.Agglutination confirmed 'Du’ otherwise it was confirmed as D (-). Results: Out of the 50 D?negative women subjectedto the indirect antiglobulin test 6 women were found to have Du’ blood. Conclusions: This reflects a significantpercentage of D' negative. Du' subjects in our obstetrics patients. Therefore, utmost care should be taken beforelabeling a subject D' negative.


Shapiro M. The ABO. MNP and Rh Blood

group systems in the South African Bantu.

S.Afr. Med. J. 1951: 25: 1X7

Argali Cl, Ball.JM and Trentloman F.

Presence of anti-D antibody in the serum of a

Du Patient J. lab. Clin. Med. 1953: 41: 895

Schneder J. German Trials in proceedings of

symposium on Rh antibody

immunosuppression. Roritan, New Jersey.

: Ortho Research Institute. 63.

Davey, M.G: Epidemiology of failure of RG

immunoglobulin and ABO protection, in

proceedings of symposium on Rh. antibody

Mediated immunosuppression, Raritan, New

Jersey, 1976: Ortho Research Institute 109.

Issitt PD. Serology and Genetics of the

Rhesus Blood Group system. Cincinnati.

Ohio: 1979 Montgomery Scientific


Rush M, Sabo B. Stroup M and Masourodis

SP. Red cells D antigen sites and titration

scores in a family with week and normal Du

phenotypes inherited from a homozygous Du

mother. Transfusion 1974; 14:433

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