INCIDENCE OF ‘Du’ IN ‘Rh’ NEGATIVE OBSTETRICS PATIENTS
AbstractBackground: A small number of persons with Rh-negative blood have red blood cells that are not directly agglutinatedby anti D during routine testing for 'Rh' antigen, but that do react when the D-typing test is converted to the indirectantiglobulin test, which is Du' test. Cells thus identified are then designated as 'Du' cells. This study was done to assessthe incidence of ‘Du’ patients in Rh negative obstetrics patients. Methods: A total of 1500 pregnant women werescreened for Rh antigen. The red blood cells of the D negative subjects were then tested by indirect method.Agglutination confirmed 'Du’ otherwise it was confirmed as D (-). Results: Out of the 50 D?negative women subjectedto the indirect antiglobulin test 6 women were found to have Du’ blood. Conclusions: This reflects a significantpercentage of D' negative. Du' subjects in our obstetrics patients. Therefore, utmost care should be taken beforelabeling a subject D' negative.
Shapiro M. The ABO. MNP and Rh Blood
group systems in the South African Bantu.
S.Afr. Med. J. 1951: 25: 1X7
Argali Cl, Ball.JM and Trentloman F.
Presence of anti-D antibody in the serum of a
Du Patient J. lab. Clin. Med. 1953: 41: 895
Schneder J. German Trials in proceedings of
symposium on Rh antibody
immunosuppression. Roritan, New Jersey.
: Ortho Research Institute. 63.
Davey, M.G: Epidemiology of failure of RG
immunoglobulin and ABO protection, in
proceedings of symposium on Rh. antibody
Mediated immunosuppression, Raritan, New
Jersey, 1976: Ortho Research Institute 109.
Issitt PD. Serology and Genetics of the
Rhesus Blood Group system. Cincinnati.
Ohio: 1979 Montgomery Scientific
Rush M, Sabo B. Stroup M and Masourodis
SP. Red cells D antigen sites and titration
scores in a family with week and normal Du
phenotypes inherited from a homozygous Du
mother. Transfusion 1974; 14:433
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.