• Muhammad Tayyab
  • Muhammad Abdullah
  • Allah Ditta


Background: Thalassaemia is among the most common genetic diseases of man and the commonest inherited disorderin our country. This study was carried out to assess the lipid pattern in thalassaemic patients and to find out anysignificant variation in lipid pattern of these patients. Methods: Eighty thalassaemic patients (Group A) were selectedfrom various blood transfusion centers and hospitals. Fifty, age and sex matched, normal controls (Group B) were alsoincluded in the study. 3.0 ml blood was drawn aseptically from the antecubital vein of each subject. The serum wasseparated and stored at 4°C till analysed. Serum total cholesterol (TC) and triglycerides (TG) of all the subjects wereestimated using the commercially available kits. Results: There was a statistically significant difference (P<0.05) inthe serum TC concentrations of thalassaemic patients as compared to those of normal controls. Scrum TG levels ofthalassaemic patients were raised as compared to those of normal controls (though not statistically significant).Conclusion: There is a need to design a larger study to evaluate the real status of lipids and lipoprotein subtractions inthalassaemic patients.


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