GL YCOHEM OG LOB IN AND INCIDENCE OF CORONARY HEART DISEASE

Authors

  • Nargis Jamil
  • Mohammad Shafiq
  • Kausar Tasneem
  • Ghosia Lutfullah
  • Jamil ur Rehman

Abstract

Background: Presence of glucose on Hb1-c is established and represents a post translational glycosylation by a slow
non-enzymatic process occurring during the 120 days' life span of RBCs. It is an indicator of long term glycemic
control. Glycohemoglobin is directly related to blood glucose level. Methods: 50 randomly selected diabetic patients
were included and divided into two groups B and C of 25 subjects each. The subjects of group C were the diabetics
who were confirmed cases of CHD. while group B were the diabetics without any complications. Group A consisted
of healthy controls (n=25). Glycohemoglobin was determined by column chromatography while blood glucose was
estimated by enzymatic method. Results: Blood glucose was increased in both the patient groups (p<0.001).
Comparison of HbA| revealed a highly significant rise (p<0.001) in both the groups against normal control subjects
of group A. Correlation of Hb1-c with glucose in all the three groups was directly positive (r=+0.4). Conclusions: The
results of the present study suggest an association between HbA1-c hyperglycemia and the incidence of CHD in
diabetics.

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How to Cite

1.
Jamil N, Shafiq M, Tasneem K, Lutfullah G, Rehman J ur. GL YCOHEM OG LOB IN AND INCIDENCE OF CORONARY HEART DISEASE. J Ayub Med Coll Abbottabad [Internet]. 2000 Jan. 29 [cited 2025 Jul. 3];12(2). Available from: https://jamc.ayubmed.edu.pk/index.php/jamc/article/view/5196

Issue

Vol. 12 No. 2 (2000): JOURNAL OF AYUB MEDICAL COLLEGE, ABBOTTABAD

Section

ORIGINAL ARTICLE

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