FREQUENCY OF DIABETES MELLITUS IN PATIENTS WITH ACUTE KIDNEY INJURY UNDERGOING CORONARY ARTERY BYPASS GRAFTING
Abstract
Background: Diabetes mellitus has a major role in developing acute kidney injury (AKI) in patients undergoing coronary artery bypass grafting (CABG). The study was conducted with the aim to determine the frequency of diabetics in patient developing AKI among patients undergoing CABG. Methods: This cross-sectional study included 120 consecutive patients from Punjab Institute of Cardiology who underwent CABG from March 2018 to May 2018. At the end 101 patients were included for analysis as the rest had missing data. SPSS 20.0 was used to analyse the data. Results: A total of 101 patients were analysed among whom, 52% developed AKI, 34 (33.6%) of the patients with co-morbidity of diabetes mellitus developed acute kidney injury whereas 20 (19%) of the patients without diabetes mellitus developed AKI (Odds Ratio=2.5, 95% CI 1.04 to 6.05, p=0.024).Conclusion: The study concluded that the risk of AKI is significantly higher among patients with diabetes mellitus undergoing CABG.Keywords: Acute kidney injury (AKI); Coronary arteries bypass grafting (CABG); Diabetes mellitusReferences
Al-Nozha MM, Ismail HM, Al Nozha OM. Coronary artery disease and diabetes mellitus. J Taibah Univ Med Sci 2016;11(4):330–8.
Lu X, Huang Y, Zhang H, Zhao J. Effect of diabetes mellitus on the quality and cytokine content of human semen. J Reprod Immunol 2017;123:1–2.
Aronson D, Edelman ER. Coronary artery disease and diabetes mellitus. Cardiol Clin 2014;32(3):439–55.
Duran-Salgado MB, Rubio-Guerra AF. Diabetic nephropathy and inflammation. World J Diabetes 2014;5(3):393–8.
Yakush Williams JK. Management Strategies for Patients with Diabetic Kidney Disease and Chronic Kidney Disease in Diabetes. Nurs Clin North Am 2017;52(4):575–87.
Sharaf EI Din UAA, Salem MM, Abdulazim DO. Diabetic nephropathy: Time to withhold development and progression-A review. J Adv Res 2017;8(4):363–73.
Hertzberg D, Sartipy U, Holzmann MJ. Type 1 and type 2 diabetes mellitus and risk of acute kidney injury after coronary artery bypass grafting. Am Heart J 2015;170(5):895–902.
Hong S, Youn YN, Yoo KJ. Metabolic syndrome as a risk factor for postoperative kidney injury after off-pump coronary artery bypass surgery. Circ J 2010;74(6):1121–6.
Rydén L, Ahnve S, Bell M, Hammar N, Ivert T, Holzmann MJ. Acute kidney injury following coronary artery bypass grafting: early mortality and postoperative complications. Scand Cardiovasc J 2012;46(2):114–20.
Rydén L, Ahnve S, Bell M, Hammar N, Ivert T, Sartipy U, et al. Acute kidney injury after coronary artery bypass grafting and long-term risk of myocardial infarction and death. Int J Cardiol 2014;172(1):190–5.
Liotta M, Olsson D, Sartipy U, Holzmann MJ. Minimal changes in postoperative creatinine values and early and late mortality and cardiovascular events after coronary artery bypass grafting. Am J Cardiol 2014;113(1):70–5.
Chew ST, Ng RR, Liu W, Chow KY, Ti LK. Acute kidney injury increases the risk of end-stage renal disease after cardiac surgery in an Asian population: a prospective cohort study. BMC Nephrol 2017;18(1):60.
Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, et al. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007;11(2):R31.
Leavitt BJ, Sheppard L, Maloney C, Clough RA, Braxton JH, Charlesworth DC, et al. Effect of diabetes and associated conditions on long-term survival after coronary artery bypass graft surgery. Circulation 2004;110(11 suppl 1):II41–4.
Pacini D, Pantaleo A, Di Marco L, Leone A, Barberio G, Parolari A, et al. "Risk factors for acute kidney injury after surgery of the thoracic aorta using antegrade selective cerebral perfusion and moderate hypothermia." J Thorac Cardiovasc Surg 2015;150(1):127–33.
Panton UH, Bagger M, Barquera S. Projected diabetes prevalence and related costs in three North American urban centres (2015–2040). Public Health 2018;157:43–9
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