TREATMENT OF BREAST CANCER; REVIEW AND UPDATES

Authors

  • Muhammad Furrukh SHIFA CANCER CENTER SHIFA INTERNATIONAL HOSPITAL Sector H-8/4 ISLAMABAD, PAKISTAN.
  • Asim Qureshi SHIFA International Hospital PO box 8460, H-8/4, Islamabad, Pakistan. Phone: +92 336 5893329

Abstract

Cancer of the breast is the leading female cancer accounting for one fourth of the malignancies. The tumour remains the most researched, read and practiced upon around the Globe. The treatment has substantially improved breast cancer related outcomes, both for early as well as late stages with substantial improvements in disease free and overall survival. Therapeutic decisions not only rest on clinical & tumour characteristics, but also with the evolution of molecular biology and tissue microarray intrinsic sub-types have been found. Attempts are being made to translate therapy from genomic architecture of individual breast cancer. This facilitates customization of treatment avoiding un-necessary toxicity, costs and inconvenience. Optimizing treatment based on individual breast biology seems logical and allows unifying treatment. The paper reviews literature, incorporate updates and also describes immunohistochemistry based molecular classification: which are found simple to adapt, record, present and subsequently manage, summarizing clinical practices in management of these patients.  Keywords: Breast; Cancer; Molecular biology; Triple negative; Immunohistochemistry; Receptor, erb-B2;Therapy; Antibodies, Monoclonal

Author Biographies

Muhammad Furrukh, SHIFA CANCER CENTER SHIFA INTERNATIONAL HOSPITAL Sector H-8/4 ISLAMABAD, PAKISTAN.

Assistant ProfessorSHIFA College of MedicineConsultant Radiation OncologistDept. Of Radiation OncologySHIFA Cancer CENTER  

Asim Qureshi, SHIFA International Hospital PO box 8460, H-8/4, Islamabad, Pakistan. Phone: +92 336 5893329

Associate Consultant PathologistDept. of Pathology

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2018-04-17