ORAL CORTICOSTEROID THERAPY FOR SUDDEN SENSORINEURAL HEARING LOSS AND FACTORS AFFECTING PROGNOSIS
AbstractBackground: Sudden sensorineural hearing loss (SSNHL) is considered an otologic emergency globally. Aetiology is unknown in most cases but still the disease is believed to be caused by inflammation of the cochlea; therefore, steroids are considered beneficial due to their anti-inflammatory effect. Methods: This study was conducted on 62 patients of sudden sensorineural hearing loss (SSNHL) in Ayub Medical Complex, Abbottabad. The patients were given prednisolone and their response to the therapy was monitored. Factors like age of the patient, gender, degree of hearing loss and duration of symptoms at initial presentation were recorded and their effect of response of the patient was also noted. Results: The research subjects were 62 patients. Majority of the patients suffered from moderate to moderately severe hearing loss. Age and gender did not influence the response to the treatment. While the patients who presented earlier after the onset of disease and the patients who had milder degree of hearing loss at presentation had a better response to therapy. Conclusion: Oral corticosteroid therapy is a good therapeutic option for the treatment of sudden sensorineural hearing loss (SSHNL). The response to therapy is better in patients with milder hearing loss and those who present early to the otologist for treatment.
Hwang GH, Joo JW, Song IS, Rah YC, Choi J. Questionnaires in Patients with Unilateral Sudden Sensorineural Hearing Loss. J Int Adv Otol 2017;13(2):211–6.
Xie Y, Orabi NA, Zwolan TA, Basura GJ. Outcomes of unilateral idiopathic sudden sensorineural hearing loss: Two decades of experience. Laryngoscope Investig Otolaryngol 2019;4(6):693–702.
Jensen EAH, Harmon ED, Smith W. Early identification of idiopathic sensorineural sudden hearing loss. Nurse Pract 2017;42(9):10–6.
Shim HS, Joon SK, Kim MG. Comparative analysis of the combined therapeutic effects of lipoprostaglandin E1 on sudden idiopathic sensorineural hearing loss. J Adiol Otol 2017;21(1):33–8.
Zanetti D, Berardino F, Nassif N, Zinis LRD. Intratympanic steroid delivery by an indwelling catheter in refractory severe sudden sensorineural hearing loss. Auris Nasus Larynx 2018;45(2):227–33.
Khater A, El-Anwar MW, Nofal AAF. Elbahrawy AT. Sudden sensorineural hearing loss: Comparative study of different treatment modalities. Int Arch Otorhinolaryngol 2018;22(3):245–9.
Okada M, Hato N, Nishio S, Kitoh R, Ogawa K, Kanzaki S, et al. The effect of initial treatment on hearing prognosis in idiopathic sudden sensorineural hearing loss: a nationwide survey in Japan. Acta Otolaryngol 2017;137:30–3.
Hosokawa S, Sugiyama K, Takahashi G, Takebayashi S, Mineta H. Prognostic factors for idiopathic sudden sensorineural hearing loss treated with hyperbaric oxygen therapy and intravenous steroids. J Laryngol Otol 2017;131(1):77–82.
Kosta M, Drsata J, Blaha M, Lanska M, Chrobok V. Rheopheresis in treatment of idiopathic sudden sensorineural hearing loss. J Otolaryngol Head Neck Surg 2017;46(1):50.
Yoshida T, Sone M, Kitoh R, Nishio S, Ogawa K, Kanzaki S, et al. Idiopathic sudden sensorineural hearing loss and acute low tone sensorineural hearing loss: a comparison of the results of a nationwide epidemiological survey in Japan. Acta Otolaryngol 2017;137:38–43.
Stacheler RJ, Chandrasekhar SS, Archer MS, Rosenfeld RM, Schwartz SR, Barrs DM, et al. Clinical practice guideline: sudden hearing loss. Otolaryngol Head Neck Surg 2012;146(3 Suppl):1–35.
Gallo DE, Khojasteh E, Gloor M, Hegemann SCA. Effectiveness of systemic high dose dexamethasone therapy for sudden sensorineural hearing loss. Audio Neurotol 2013;18(3):161–70.
Chen WT, Lee JW, Yuan CH, Chen RF. Oral steroids treatment for idiopathic sudden sensorineural hearing loss. Saudi Med J 2015;36(3):291–6.
Kitoh R, Nishio S, Ogawa K, Kanzaki S, Naohito H, Sone M, et al. Nationwide epidemiological survey of idiopathic sudden sensorineural hearing loss in Japan. Acta Otolaryngo 2017;137:8–16.
Kang WS, Yang CJ, Shim M, Song C, Kim TS, Lim HW, et al. Prognostic factors for recovery from sudden sensorineural hearinh loss: A retrospective study. J Audiol Otol 2017;21(1):9–15.
Weiss D, Bocker AJ, Koopmann M, Savvas E, Borowski M, Rudack C. Predictors of hearing recovery in patients with severe sudden sensorineural hearing loss. J Otolaryngol Head Neck Surg 2017;46(1):27.
Conlin AE, Parnes LS. Treatment of sudden sensorineural hearing loss: A systematic reciew. Arch Otolaryngol Head Neck Surg 2007;133(6):573–81.
Chandrasekhar SS. Intratympanic dexamethasone for sudden sensorineural hearing loss: clinical and laboratory evaluation. Otol Neurotol 2001;22(1):18–23.
Singh A, Irugu DVK. Sudden sensorineural hearing loss. A contemporary review of management issues. J Otol 2020;15(2):67–73.
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