THE EFFECT OF PRE-MEDICATION WITH ORAL STEROIDS ON INTRA-OPERATIVE BLEEDING IN PATIENTS WITH CHRONIC RHINOSINUSITIS UNDERGOING FUNCTIONAL ENDOSCOPIC SINUS SURGERY

Authors

  • Saira Iftikhar Shifa College of Medicine, Islamabad-Pakistan
  • Ayesha Jawad Shifa College of Medicine, Islamabad-Pakistan
  • Mumtaz Ahmad Umar Islamabad Medical and Dental College, Islamabad-Pakistan
  • Farhan Ahmed HITEC Institute of Medical Sciences, Taxila-Pakistan
  • Maimoona Shafqat Shifa College of Medicine, Islamabad-Pakistan
  • Seema Naveed Shifa College of Medicine, Islamabad-Pakistan

DOI:

https://doi.org/10.55519/JAMC-03-13602

Keywords:

Oral Steroids, Per-Operative Bleeding, Blood Loss

Abstract

Background: An inflammation of the nasal and paranasal sinus mucosa that lasts longer than three months is known as chronic rhinosinusitis. When corticosteroids and other medicinal treatments fail to relieve a patient's symptoms, then functional endoscopic sinus surgery (FESS) is a commonly performed procedure to alleviate the symptoms. The aim of the study was to evaluate the impact of oral steroids given prior to surgery on intraoperative bleeding in patients having functional endoscopic sinus surgery for chronic rhinosinusitis. Methods: The study was conducted in ENT Department of Shifa Foundation Community Health Centre (SFCHC) and Shifa International Hospital (SIH) Islamabad, in a period of three years from June 2019 to June 2021. A total of 72 patients consisting of 36 patients in study group and 36 in control group, fulfilling the inclusion criteria were included in the study. Per-operative bleeding was assessed by measuring the amount of blood collected in suction bottle at the end of the procedure (the amount of saline used during the procedure was subtracted) and the number of surgical gauzes stained with blood (1 partially stained gauze = 5 ml and 1 completely stained gauze = 10 ml). The surgeon performing the surgery was unaware of the study group of the patient. All the collected data was entered and analyzed with SPSS v. 25. Results: The mean age of group A (35.39±13.86 vs. 29.83±15.86, p-value > 0.05) was similar to group B. There was male dominance in both group (69.4% vs. 72%) males in group A and group B. Nasal obstruction and nasal discharge was observed in all patients of both groups. Post nasal drip (88.9% vs. 88.9%), headache (97.2% vs. 91.7%) and facial pain (97.2% vs. 94.4%) was present in majority patients of both groups without any significant (p-value >0.05) difference. Both the groups were compared on the basis of amount of blood loss per-operatively and it was seen that the mean blood loss in group A was (164.03±42.99 ml) significantly (p-value <0.05) lower as compared to (215.83±39.397 ml) in group B. Conclusion: This study showed that individuals with nasal polyps receiving preoperative steroids could successfully lower their perioperative morbidity, specifically intraoperative haemorrhage, after undergoing functional endoscopic sinus surgery.

References

Fraire ME, Sanchez-Vallecillo MV, Zernotti ME. Effect of premedication with systemic steroids on surgical field bleeding and visibility during nasosinusal endoscopic surgery. Acta Otorrinolaringol Esp. 2013; 64(2):133-9.

Hong SJ, Lee JK, Lee HS, Lee JY, Pyo JS, Lee KC. Availability of preoperative systemic steroids on endoscopic sinus surgery for chronic sinusitis with nasal Polyposis. Yonsei Med J. 2014; 55(6):1683-90.

Lux CA, Wagner Mackenzie B, Johnston J, Zoing M, Biswas K, Taylor MW et al. Antibiotic treatment for chronic rhinosinusitis: prescription patterns and associations with patient outcome and the sinus microbiota. Front Microbiol. 2020; 11:595555.

Varshney H, Varshney J, Biswas S, Ghosh SK. Importance of CT scan of paranasal sinuses in the evaluation of the anatomical findings in patients suffering from sinonasal polyposis. Indian J Otolaryngol Head Neck Surg. 2016; 68(2):167-72.

Abbate V, Iaconetta G, Maglitto F, Improta G, Romano A, Bonavolonta P et al. A comparative study of different administrations of nebulized hyaluronic acid after endoscopic endonasal surgery for chronic rhinosinusitis. Indian J Otolaryngol Head Neck Surg. 2022; 74(2):1037-43.

Sudheer CP, Sing TD. Assess the outcome of pre and postoperative bacterial culture in sinonasal polyposis cases under FESS. Int J Otorhinolaryngol Head Neck Surg. 2019; 5(2):373-6.

Kaski HM, Alakarppa A, Lantto U, Laajala A, Tokola P, Penna T et al. Endoscopic sinus surgery (ESS) to change quality of life for adults with recurrent rhinosinusitis: study protocol for a randomized controlled trial. Trials. 2021; 22:606.

Albu S, Gocea A, Mitre I. Preoperative treatment with topical corticoids and bleeding during primary endoscopic sinus surgery. Otolaryngol Head Neck Surg 2010; 143:573- 8.

Yasir M, Goyal A, Sonthalia S. Corticosteroid Adverse Effects. [Updated 2022 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from:https://www.ncbi.nlm.nih.gov/books/NBK531462/

Gunel c, BaÅŸak HS, Bleier BS. Oral steroids and intraoperative bleeding during endoscopic sinus surgery. B-ENT. 2015; 11:123-8.

Fraire ME, Sanchez-Vallecillo MV, Zernotti ME, Paoletti OA. Effect of premedication with systemic steroids on surgical field bleeding and visibility during nasosinusal endoscopic surgery. Acta Otorrinolaringol Esp. 2013 Mar-Apr; 64(2):133-9.

Ali Algadiem E, Aleisa AA, Alsubaie HI, Buhlaiqah NR, Algadeeb JB, Alsneini HA. Blood loss estimation using gauze visual analogue. Trauma Mon. 2016 May 3; 21(2):e34131.

Hwang SH, Seo JH, Joo YH, Kang JM. Does the preoperative administration of steroids reduce intraoperative bleeding during endoscopic surgery of nasal polyps? Otolaryngol Head Neck Surg. 2016; 155(6):949-55.

Khan KA, Raza M, Najam A, Faiz SB. Effect of preoperative steroids on perioperative and postoperative hemorrhage in patients undergoing FESS. Pak Armed Forces Med J. 2013; 63(1):46-9.

Khosla AJ, Pernas FG, Maeso PA: Meta-analysis and literature review of techniques to achieve hemostasis in endoscopic sinus surgery. Int Forum Allergy Rhinol. 2013; 3:482-7.

Pundir V, Pundir J, Lancaster G. Role of corticosteroids in functional endoscopic sinus surgery - a systematic review and meta-analysis. Rhinology. 2016; 54(1):3-19.

Pathak RK, Kumar N, Mohit Bagde M. A Study on the effect of preoperative systemic corticosteroids on intraoperative outcome in patients undergoing functional endoscopic sinus surgery for Sinonasal Polyposis. IOSR J Dent Med Sci. 2020; 19(1):19-24.

Jagannath B, Pillai N, Bharath KKL. Comparative study on the effects of pre-operative intranasal steroid spray versus oral steroid on intraoperative bleed in FESS for nasal polyposis. Int J Otorhinolaryngol Head Neck Surg 2021; 7:782-8.

Downloads

Published

2024-09-08

How to Cite

Saira Iftikhar, Ayesha Jawad, Mumtaz Ahmad Umar, Farhan Ahmed, Maimoona Shafqat, & Seema Naveed. (2024). THE EFFECT OF PRE-MEDICATION WITH ORAL STEROIDS ON INTRA-OPERATIVE BLEEDING IN PATIENTS WITH CHRONIC RHINOSINUSITIS UNDERGOING FUNCTIONAL ENDOSCOPIC SINUS SURGERY. Journal of Ayub Medical College Abbottabad, 36(3), 564–568. https://doi.org/10.55519/JAMC-03-13602

Similar Articles

<< < 2 3 4 5 6 7 8 9 10 11 > >> 

You may also start an advanced similarity search for this article.