MAGNESIUM SUPPLEMENTATION IN CYSTIC FIBROSIS; SAVING AN INFANT
Abstract
Hypo-magnesaemia is an under diagnosed condition in patients of cystic fibrosis. Here a case is reported of an imminent complete respiratory failure, which was avoided by the timely administration of Magnesium Sulphate. The case report is followed by a brief recent literature search about hypo magnesaemia and perioperative management of cystic fibrosis.References
Huffmyer JL, Littlewood KE, Nemergut EC. Perioperative management of the adult with cystic fibrosis. Anesth Analg 2009;109(6):1949–61.
Gontijo-Amaral C, Guimarães EV, Camargos P. Oral magnesium supplementation in children with cystic fibrosis improves clinical and functional variables: a double-blind, randomized, placebo-controlled crossover trial. Am J Clin Nutr 2012;96:50–6.
Nievas IF, Anand KJ. Severe acute asthma exacerbation in children: a stepwise approach for escalating therapy in a pediatric intensive care unit. J Pediatr Pharmacol Ther 2013;18(2):88–104.
Godson C1, Ryan MP, Brady HR, Burke S, FitGerald MX. Acute hypomagnesaemia complicating the treatment of meconium ileus equivalent in cystic fibrosis. Scand J Gastroenterol Suppl 1988;23:148–50.
Rowe BH, Bretzlaff JA, Bourdon C, Bota GW, Camargo CA Jr. Magnesium sulfate for treating exacerbations of acute asthma in the emergency department. Cochrane Database Syst Rev 2000;(2):CD001490.
Gupta A, Eastham KM, Wrightson N, Spencer DA. Hypomagnesaemia in cystic fibrosis patients referred for lung transplant assessment. J Cyst Fibros 2007;6(5):360–2.
Shan Z, Rong Y, Yang W, Wang D, Yao P, Xie J, et al. Intravenous and nebulized magnesium sulfate for treating acute asthma in adults and children: a systematic review and meta-analysis. Respir Med 2013;107(3):321–30.
Akbar A, Rees JH, Nyamugunduru G, English MW, Spencer DA, Weller PH. Aminoglycoside-associated hypomagnesaemia in children with cystic fibrosis. Acta Paediatr 1999;88(7):783–5.