• Iram Sarwar
  • Ruqqia Sultana
  • Rahat Un Nisa
  • Iftikhar Qayyum


Background: Vaginal agenesis is congenital anomaly of the female genital tract and may occur asisolated developmental defect or as part of a complex of anomalies. The aim of this study was todetermine the effectiveness of vaginoplasty by using amnion as graft in the creation of neovagina forpatients with Mayor-Rokitansky-Kuster-Hauser Syndrome. Methods: this is a retrospective study of 28cases of vaginal agenesis associated with Mayor-Rokitansky-Kuster-Hauser Syndrome, over the periodof 20 years, in which vaginoplasty was done by modified McIndoe procedure by using amnion as graft.Results: vaginoplasty using amnion graft was successfully performed in all except one case in whichrectum got opened and procedure was abandoned after the repair of rectum. The functional results werequite satisfactory. Except one case none had any significant peri-operative complication. Post surgicalresults were acceptable to the patients sexually and aesthetically. Conclusion: Although newtechniques of vaginoplasty have evolved over the years using laparoscopic approach and by use ofdifferent materials as graft, vaginoplasty with amnion graft is still a safe and effective procedure to treatpatients of vaginal agenesis. The technique is simple and safe and provides a satisfactory and functionalvagina in majority of the patients.Keywords: vaginoplasty, amnion graft, vaginal agenesis, vaginal atresia, Mayor-RokitanskyKuster-Hauser Syndrome


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