• Ghulam Mujadid Qureshi
  • Ghulam Mustafa Seehar
  • Mevo Khan Zardari
  • Zafar Ali Pirzado
  • Siraj Ahmed Abbasi


Background: Increased cholesterol in blood plays the role in atherosclerosis formation. It is observedthat stress increases cholesterol level. Most of previous studies were conducted on biological riskfactors like blood lipids under stress in middle aged persons who remained under investigations forheart problems. Objective: The study was conducted to evaluate the changes in blood lipids and bloodcortisol along with sympatheo-adnergic responses determined by selected haemodynamic parametersduring psychological stress. Methods: Male participants (n=114) were randomly selected. They wereexamined two times, for stress task of viva-voce (degree examination) and during non-stress period.Final selection of participants was depending on stress assessment and their well being. Results:Cortisol, systolic and diastolic blood pressures (SBP and DBP) and heart rate (HR) were significantlyincreased during stress period with p<0.001 for each parameter. But different blood lipids levels (TC,LDL-C, HDL-C and TG) were detected with different significant levels. The correlations of changedlipids with raised findings of haemodynamics and cortisol were also evaluated. Conclusion: Furtherstudies in our population are needed to evaluate the relation of changes in various biological risk factorsincluding IL-9 and sympatho-adernergic activities with stress factors related to our social/environmental problems, especially genetically based psychological factors.Keywords: Cholesterols, Haemodynamics, Cortisol, psychological stress.


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